ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser +6 more
wiley +1 more source
Rationale, design and conduct of a randomised controlled trial evaluating a primary care-based complex intervention to improve the quality of life of heart failure patients: HICMan (Heidelberg Integrated Case Management) : study protocol [PDF]
Background: Chronic congestive heart failure (CHF) is a complex disease with rising prevalence, compromised quality of life (QoL), unplanned hospital admissions, high mortality and therefore high burden of illness. The delivery of care for these patients
A Steptoe +44 more
core +3 more sources
Assessing the relationship between neighborhood factors and diabetes related health outcomes and self-care behaviors [PDF]
Studies have shown that community and neighborhood characteristics can impact health outcomes of those with chronic illness, including T2DM. Factors, such as crime, violence, and lack of resources have been shown to be barriers to optimal health outcomes in diabetes.
Smalls, Brittany L. +3 more
openaire +2 more sources
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd +3 more
wiley +1 more source
School-age effects of the newborn individualized developmental care and assessment program for preterm infants with intrauterine growth restriction: preliminary findings [PDF]
Background: The experience in the newborn intensive care nursery results in premature infants’ neurobehavioral and neurophysiological dysfunction and poorer brain structure.
Alidoost, Moona +10 more
core +1 more source
Level Assessments of Learning Outcomes in Health Care and Nursing
Das Leonardo da Vinci-Innovationstransferprojekt CrediCare verfolgte das Ziel der grenzüberschreitenden Übertragung und Erprobung eines Verfahrens zur Beschreibung und vergleichenden Niveaubestimmung von Lernergebnissen des Pflegesektors. Das Verfahren ist so konzipiert, dass seine Anwendung in Ländern mit unterschiedlichen Berufsbildungssystemen ...
openaire +2 more sources
Diversity and Regional Inequalities: Assessing the Outcomes of the Spanish 'System of Health Care Services' [PDF]
The consolidation of a universal health system coupled with a process of regional devolution characterise the institutional reforms of the National Health System (NHS) in Spain in the last two decades. However, scarce empirical evidence has been reported on the effects of both changes in health inputs, outputs and outcomes, both at the country and at ...
Guillem López +2 more
openaire +4 more sources
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez +13 more
wiley +1 more source
Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack +12 more
wiley +1 more source
The dynamics of quality: a national panel study of evidence-based standards [PDF]
This is the final version of the article. Available from NIHR Health Technology Assessment Programme via the DOI in this record.Background Shortfalls in the receipt of recommended health care have been previously reported in England, leading to ...
+65 more
core +1 more source

