Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani +8 more
wiley +1 more source
What are patients' and healthcare professionals' views on managing penicillin allergy? A qualitative evidence synthesis. [PDF]
Kildonaviciute K +4 more
europepmc +1 more source
ABSTRACT Objective Status epilepticus (SE) is associated with significant mortality. Sleep architecture may reflect normal brain function. Impaired sleep architecture is associated with poorer outcomes in numerous conditions. Here we investigate the association of sleep architecture in continuous EEG (cEEG) with survival in SE.
Ran R. Liu +5 more
wiley +1 more source
Digital Health in Pediatric Oncology and Hematooncology: A Quasi-Systematic Review of Telehealth, mHealth and Precision Medicine. [PDF]
Ziętara KJ +4 more
europepmc +1 more source
Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker +9 more
wiley +1 more source
Effectiveness of digital health interventions for increasing preventive care for smoking, nutrition, alcohol consumption, physical activity and weight (SNAP-W) in outpatient settings: a systematic review protocol. [PDF]
Farragher E +6 more
europepmc +1 more source
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick +14 more
wiley +1 more source
PRECEDE-PROCEED model for discharge preparation in first-cycle colorectal cancer chemotherapy: a quasi-experimental study. [PDF]
Chen X +6 more
europepmc +1 more source
From Promise to Practice: Harmonizing Telemedicine in Pediatric Chronic Respiratory Diseases. [PDF]
Esposito S +3 more
europepmc +1 more source

