Results 211 to 220 of about 12,158,807 (343)

Assessment of Student Learning Outcomes and ABET Accreditation: A Pilot Study of Fourth-Year Engineering Students using Longitudinal Concept Maps [PDF]

, 2018
Sean Ferguson, Rider W. Foley
openalex   +1 more source

Group for Research and Assessment of Psoriasis and Psoriatic Arthritis/Outcome Measures in Rheumatology Consensus‐Based Recommendations and Research Agenda for Use of Composite Measures and Treatment Targets in Psoriatic Arthritis

Arthritis & Rheumatology, 2018
L. Coates, O. FitzGerald, J. Merola, J. Smolen, L. V. van Mens, H. Bertheussen, W. Boehncke, K. Callis Duffin, Willemina Campbell, M. D. de Wit, D. Gladman, A. Gottlieb, J. James, A. Kavanaugh, L. Kristensen, T. Kvien, T. Luger, N. McHugh, P. Mease, P. Nash, A. Ogdie, C. Rosen, V. Strand, W. Tillett, D. Veale, P. Helliwell   +25 more
semanticscholar   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Seymour fracture management and functional outcome assessment: a case report. [PDF]

J Surg Case Rep
Ortega VHG, Terán AIS.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Testing the applicability of a governance checklist for high-risk AI-based learning outcome assessment in Italian universities under the EU AI act annex III. [PDF]

Front Artif Intell
Manganello F, Nico A, Ragusa M, Boccuzzi G.   +3 more
europepmc   +1 more source

Assessment of outcome in clinical trials in mild Alzheimer�s disease: Urgent time for a rethink?

, 2013
Yvonne Morrison, Lindsay Wilson, Fiona Kelly, Cathy Bennett, Fergal J. Duffy, Sean J.F. McGoldrick, Emma Reynish   +6 more
openalex   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Multiparametric Outcome Assessment After Transcatheter Aortic Valve Implantation-A Systematic Review. [PDF]

J Clin Med
Świątoniowska-Lonc N, Klausa F, Ściborski K, Wysokińska-Kordybach A, Banasiak W, Doroszko A.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source