Results 51 to 60 of about 11,004,439 (292)

Clinical and cost-effectiveness of spironolactone in treating persistent facial acne in women: SAFA double-blinded RCT

Health Technology Assessment
Background Acne is common, can cause significant impact on quality of life and is a frequent reason for long-term antibiotic use. Spironolactone has been prescribed for acne in women for many years, but robust evidence is lacking.
Miriam Santer, Megan Lawrence, Sarah Pyne, Susanne Renz, Beth L Stuart, Tracey Sach, Matthew Ridd, Kim S Thomas, Jacqueline Nuttall, Natalia Permyakova, Zina Eminton, Nick Francis, Paul Little, Ingrid Muller, Irene Soulsby, Karen Thomas, Gareth Griffiths, Alison M Layton   +17 more
doaj   +1 more source

Impact of 25-Hydroxyvitamin D on the Prognosis of Acute Ischemic Stroke: Machine Learning Approach

Frontiers in Neurology, 2020
Background and Purpose: Vitamin D is a predictor of poor outcome for cardiovascular disease. We evaluated whether serum 25-hydroxyvitamin D level was associated with poor outcome in patients with acute ischemic stroke (AIS) using machine learning ...
Chulho Kim, Chulho Kim, Sang-Hwa Lee, Jae-Sung Lim, Yerim Kim, Min Uk Jang, Mi Sun Oh, San Jung, Ju-Hun Lee, Kyung-Ho Yu, Byung-Chul Lee   +10 more
doaj   +1 more source

Effects of autism spectrum disorders on outcome in teenage-onset anorexia nervosa evaluated by the Morgan-Russell outcome assessment schedule: a controlled community-based study

Molecular Autism, 2015
BackgroundThe purpose of the study was to evaluate time trends and effects of co-existing autism spectrum disorders (ASD) on outcome in an ongoing long-term follow-up study of anorexia nervosa (AN).MethodsThe Morgan-Russell Outcome Assessment Schedule ...
Søren Nielsen, H. Anckarsäter, C. Gillberg, Christopher Gillberg, M. Råstam, E. Wentz   +5 more
semanticscholar   +1 more source

Clinical Correlates of Anxiety and Depression After Diagnosis of a Pediatric Brain Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The prevalence and clinical correlates of symptoms of anxiety and depression in pediatric patients with brain tumors are not well described. We aimed to identify clinical characteristics that are correlated with elevated symptoms of anxiety and depression following initial diagnosis.
Bryony J. Lucas, Se‐Kang Kim, Joan Yu, Ana Sofia C. Ibarrola, Heather H. Stancel, Kavyaa Choudry, Mary Elizabeth Moody, Krystal K. Christopher, David R. Grosshans, Arnold C. Paulino, Guillermo Aldave, M. Fatih Okcu, Murali M. Chintagumpala, Austin L. Brown, Michael E. Scheurer, Kimberly P. Raghubar, Lisa S. Kahalley   +16 more
wiley   +1 more source

C-index: A novel method to assess surgical morbidity in obstetric and gynecological surgery: A retrospective study

Journal of Clinical Sciences
Background: There is a need to develop a method of assessing the outcomes of surgery that is as accurate as studying complications, more objective than patient-reported outcome measures and easier than cost-effective analysis.
Chanil Deshan Ekanayake, Arunasalam Pathmeswaran, Sakshara Ranasinghe, Amritha Sridaran, Yeshmitha Madanayake, Samurdika Nishamalee   +5 more
doaj   +1 more source

Individualised placement and support programme for people unemployed because of chronic pain: a feasibility study and the InSTEP pilot RCT

Health Technology Assessment, 2021
Background: Chronic pain is a common cause of health-related incapacity for work among people in the UK. Individualised placement and support is a systematic approach to rehabilitation, with emphasis on early supported work placement.
Cathy Linaker, Simon Fraser, Cathy Price, Nick Maguire, Paul Little, Ira Madan, Rafael Pinedo-Villanueva, David Coggon, Cyrus Cooper, Georgia Ntani, Karen Walker-Bone   +10 more
doaj   +1 more source

Oncogenic NRAS Mutation in Incipient Sarcomatous Transformation of Cystic Nephroma From a Patient With DICER1‐Related Tumor Predisposition Syndrome

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Anaplastic sarcoma of the kidney (ASK) is a DICER1‐associated malignant tumor presumed to arise in a benign precursor, pediatric cystic nephroma (PCN). However, the initial oncogenic alteration(s) associated with malignant transformation are unknown.
Nahir Cortes‐Santiago, Sarah B. Whittle, Sarah Scollon, Sharon E. Plon, Sanjeev Vasudevan, Bryony J. Lucas, Angshumoy Roy   +6 more
wiley   +1 more source

Blinded Outcome Assessment Was Infrequently Used and Poorly Reported in Open Trials

PLoS ONE, 2015
Objective Unblinded outcome assessment can lead to biased estimates of treatment effect in randomised trials. We reviewed published trials to assess how often blinded assessment is used, and whether its use varies according to the type of outcome or ...
B. Kahan, S. Rehal, S. Cro
semanticscholar   +1 more source

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano, Valerio Voglino, Federico Beati, Cristina Martucci, Chiara Grimaldi, Francesca Del Bufalo, Annalisa Serra, Francesco Fabozzi, Carmen Malaspina, Pier Luigi Di Paolo, Gian Luigi Natali, Simone Reali, Maria Antonietta De Ioris, Alessandro Crocoli   +13 more
wiley   +1 more source

Successful hearing preservation and improved subjective sound quality with the flexible 28-mm electrode array

Frontiers in Audiology and Otology
IntroductionFlexible electrode arrays have shown to be an effective solution to ensure atraumatic insertion. However, flexible full-length electrodes are not suited for patients with smaller cochleae.
Miryam Calvino, Miryam Calvino, Isabel Sánchez-Cuadrado, Elena Muñoz, Javier Gavilán, Luis Lassaletta, Luis Lassaletta   +6 more
doaj   +1 more source