Results 181 to 190 of about 3,863,870 (310)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Implementing an Optimized Perioperative Strategy for Percutaneous Vertebroplasty: Clinical Application and Outcome Evaluation. [PDF]

Orthop Surg
Zhang Z, Liu S, Shao J, Meng H, Lin J, Fei Q.   +5 more
europepmc   +1 more source

SONOGRAPHIC EVALUATION OF FIRST TRIMESTER BLEEDING AND IT'S OUTCOME

BLDE University
openalex   +1 more source

Methodological Evaluation of District Hospitals in Rwanda: A Systematic Review of Clinical Outcomes Measurement Frameworks

, 2009
Genzi Ruzindana, Gisèle Umutoni, Kizito Mukabe   +2 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Impact of the Internet Plus Health Education Model on Treatment Adherence, Disease Knowledge and Patient Satisfaction in Pulmonary Tuberculosis

Patient Preference and Adherence
Xiaofeng Chen,1,* Xin Zhang,1,* Feifei Nie,2 Xiujun Wang,3 Jiewen Zhang,2 Xiuhua Wang,4 Chen Lv3 1Department of Intensive Care Unit, Beijing Chest Hospital, Capital Medical University, Beijing, 101149, People’s Republic of China ...
Chen X, Zhang X, Nie F, Wang X, Zhang J, Wang X, Lv C   +6 more
doaj  

Comparison Between RIRS and Mini-PCNL in the Treatment of Kidney Stones Exceeding 15 mm: Outcome Evaluation and Cost Analysis. [PDF]

J Clin Med
Suraci PP, Fuschi A, Sequi MB, Valenzi FM, Antonioni A, Rera OA, Al Salhi Y, Graziani D, Martino G, Candita G, Gianfrancesco F, Benanti P, De Nunzio C, Bozzini G, Di Dio M, Russo P, Pacini M, Introini C, Carbone A, Pastore AL.   +19 more
europepmc   +1 more source

Evaluation of the functional outcome measures of recurrent clubfeet after posteromedial or posterior release treated using the Ponseti method: a preliminary study

Jing Ding, Zhenzhen Dai, Zhao Li, Zhenkai Wu   +3 more
openalex   +1 more source

Methodological Evaluation of Rural Clinics Systems in Ethiopia:Randomized Field Trial for Clinical Outcomes Measurement

, 2010
Mekdes Beyene, Tadesse Gashaw Asrat, Aregawi Mengistu   +2 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source