Results 151 to 160 of about 28,929 (254)

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

Collaborative strategies for planning post-earthquake waste disposal facilities: a bounded rationality perspective. [PDF]

Sci Rep
Yang Q, Liu S, Zhang F, Cao C, Liang L.
europepmc   +1 more source

Ga Doping Enables Precision Alloy‐to‐Wire Regulation: Synergistic Enhancement of the Mechanical Properties of CuSn Alloy and the Superconducting Properties of Nb3Sn

Advanced Science, EarlyView.
By adjusting Ga's doping in Cu–Sn alloy, an ultra‐high elongation of 100.8% is achieved in first time. Ga forms a stable solid solution structure and a stronger electron exchange with Cu. This enhances strength‐ductility synergistically by tuning SFE to balance twinning and slip.
Dazhuo Song, Juntao Zou, Jiayue Zhang, Xinhang Liang, Mengyu Shan, Yifan Liu, Jingqi Feng, Tong Dang, Lin Shi, Yuxuan Wang, Yuchen Song, Rong Fei, Shaodong Sun, Zhe Zhang, Lei Zhu, Lixing Sun   +15 more
wiley   +1 more source

A stochastic framework to assess the optimal allocation of limited vaccine doses in foot-and-mouth disease outbreaks using game theory. [PDF]

Front Vet Sci
Moreno-Torres KI, Sanderson MW, Rigney C, Schoenbaum M, Delgado A, Arzt J, Heier Stamm JL.   +6 more
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

The choice of corporate social responsibility strategies under rivalry: Whether to increase socially responsible product characteristics or enhance relationship with buyers. [PDF]

PLoS One
Zhao X.
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Effects of video game-based interventions on executive functions and motor skills in children and adolescents with neurodevelopmental disorders: a systematic review and meta-analysis. [PDF]

Front Rehabil Sci
Gao M, Ren J, Kaulie A, Wang Q, Gao G.
europepmc   +1 more source

Game theory of pandemic control: Can collaborative vaccine allocation strategies lead to better outcomes?

IJID Regions
Yiwen Wang, Yang Ye, Xiaoyi Su, Qingpeng Zhang, Hsiang-Yu Yuan   +4 more
openaire   +1 more source

Ejecta‐Modulated Bubble Dynamics Play a Dominant Role in Stone Retropulsion

Advanced Science, EarlyView.
Stone motion during laser ablation is shown to result primarily from asymmetric cavitation bubble collapse, not from ejecta recoil. This challenges long‐standing assumptions and highlights the dominant role of bubble dynamics in laser–material interactions.
Obed S. Isaac, Arpit Mishra, Georgy N. Sankin, Junqin Chen, Pei Zhong   +4 more
wiley   +1 more source