Results 151 to 160 of about 611,264 (253)

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

A Novel Interactive Outcome Based Education (OBE) Approach In Supply chain management Using Beer Game Simulation Theory

, 2013
Bahisham Yunus, S. E. S. Bariran
openalex   +1 more source

Psychological inoculation improves resilience to and reduces willingness to share vaccine misinformation. [PDF]

Sci Rep
Appel RE, Roozenbeek J, Rayburn-Reeves R, Basol M, Corbin J, Compton J, van der Linden S.   +6 more
europepmc   +1 more source

Effect of Silicon‐Based Electrolyte Additive on the Solid‐Electrolyte Interphase of Rechargeable Mg Batteries

Advanced Science, EarlyView.
In this work, a silicon‐based electrolyte additive is introduced to condition the interfaces through an activation process. Symmetric cell studies with the additive show a five‐fold decrease in interfacial resistance and over 1200 h of stable Mg plating/stripping overpotential. The full cells with Mo6S8 cathodes exhibit excellent cycling stability over
Shivaraju Guddehalli Chandrappa, Guruprakash Karkera, Sirshendu Dinda, Mario Löw, Holger Euchner, Adam Reupert, Soutam Panja, Mohan K Bhattarai, Matthias M May, Zhirong Zhao‐Karger, Maximilian Fichtner   +10 more
wiley   +1 more source

Digital Motion Graphics and Animated Media in Health Communication: A Systematic Review of Strategies for Sexual Health Messaging. [PDF]

Healthcare (Basel)
Suwanphan N, Mettarikanon D, Kaeophanuek S, Eden C, Tawanwongsri W.   +4 more
europepmc   +1 more source

Site‐Specific Mitochondrial RNA N1‐Methyladenosine Demethylation via an Engineered MTS‐PUF‐ALKBH3 Fusion Protein

Advanced Science, EarlyView.
A CRISPR‐free mitochondrial RNA m1A demethylation (MRD) editor combining MTS, PUF proteins, and ALKBH3 enables precise m1A removal from mitochondrial mRNA and tRNA, which influences mitochondrial protein levels, cellular proliferation, ATP production, and mitochondrial respiration. Subsequently, in vivo demethylation of the m1A modification is achieved
Xiangrui Li, Deqiang Kong, Hongmei Liu, Jie Yang, Jiale Zhou, Yuqiang Qian, Ding Zhao, Jinze Li, Xinyu Wu, Tao Zhang, Xiaodi Sun, Yang Han, Liangxue Lai, Zhanjun Li   +13 more
wiley   +1 more source

Contractualist Moral Cognition: From the Normative to the Descriptive at Three Levels of Analysis. [PDF]

Wiley Interdiscip Rev Cogn Sci
Le Pargneux A.
europepmc   +1 more source

A Hydrodynamic Bioreactor for High‐Yield Production of Extracellular Vesicles from Stem Cell Spheroids with Defined Cargo Profiling

Advanced Science, EarlyView.
This study harnesses hydrodynamic flows to generate, confine and stimulate stem cell spheroids, enabling the large‐scale production of extracellular vesicles (EVs). This innovative method not only streamlines spheroid formation and subsequent EV release in a single, integrated process, but also ensures the generation of EVs with enhanced biological ...
Solène Lenoir, Elliot Thouvenot, Giacomo Gropplero, Léonie Dec, Damarys Loew, Clotilde Théry, Jose E Perez, Claire Wilhelm   +7 more
wiley   +1 more source

Matrix games between full siblings in Mendelian populations. [PDF]

PLoS One
Garay J, Varga T, Csiszár V, Móri TF, Szilágyi A.   +4 more
europepmc   +1 more source

Subicular Astrocytes Govern Seizure‐Impaired Fear Memory

Advanced Science, EarlyView.
Astrocytes in dorsal subiculum act as a critical modulator of seizure‐associated cognitive dysfunction, operating through a Ca2+‐dependent adenosine‐linked astrocyte‐neuron signaling pathway that disrupts neuronal circuit homeostasis. This research highlights the potential of astrocyte‐targeted interventions as a therapeutic strategy, moving beyond the
Yuying Shao, Jing Xi, Yuhao Sun, Yulan Li, Zhisheng Li, Wangjialu Lu, Jialu Chen, Lin Yang, Fan Fei, Heming Cheng, Li Cheng, Cenglin Xu, Zhuo Huang, Vladimir Parpura, Yi Wang, Zhong Chen   +15 more
wiley   +1 more source