Results 211 to 220 of about 334,200 (306)

Carbon Catalyst Supports for Pt‐Based Polymer Electrolyte Membrane Fuel Cells: Porosity, Graphitization, and Chemical Modifications

open access: yesAdvanced Science, EarlyView.
This review explores recent advancements in understanding the influence of carbon support properties on the cathode performance of proton exchange membrane fuel cells. It proposes a set of properties deemed critical for the development of next‐generation carbon supports for the oxygen reduction reaction in fuel cells.
Camille Roiron   +5 more
wiley   +1 more source

Evolution of competitive systems in nature. [PDF]

open access: yesSci Rep
Deng C   +7 more
europepmc   +1 more source

Blocking Lysine Crotonylation and Aerobic Glycolysis as Targeting Strategy Against mpox Virus Replication

open access: yesAdvanced Science, EarlyView.
Wei et al. report that MPXV infection induces aerobic glycolysis, a process mediated by the viral protein I3 through lysine crotonylation at its K102 residue. The acetyltransferase MYST1 catalyzes the crotonylation of I3 to inhibit the ubiquitin‐mediated degradation of WDR26.
Pengjun Wei   +12 more
wiley   +1 more source

Nutritional c‐Fos Induction Rewires Hepatic Metabolism and Can Promote Obesity‐Associated Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
It is shown that hepatic c‐Fos responds to feeding, altering de novo lipogenesis, glycolysis, and a wide range of steatosis‐associated metabolic signaling pathways. Obesogenic diets cause hepatic c‐Fos overexpression, insulin resistance, and the induction of metabolic reprogramming‐related genes.
Ao Li   +8 more
wiley   +1 more source

K29‐Linked Ubiquitination of Transcription Regulators Controls Cell Proliferation in the Unfolded Protein Response

open access: yesAdvanced Science, EarlyView.
Under endoplasmic reticulum stress, cells activate the unfolded protein response (UPR). During the UPR, the cohesin complex at the promoter of cell proliferation‐related genes undergoes K29‐linked ubiquitination, recruiting the cohesin release factor WAPL to release cohesin, leading to transcriptional downregulation and inhibition of cell growth ...
Qiushuang Zhang   +5 more
wiley   +1 more source

Brinkmanship in intragenomic conflict. [PDF]

open access: yesProc Biol Sci
Kennedy P, Higginson AD.
europepmc   +1 more source

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

open access: yesAdvanced Science, EarlyView.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez   +2 more
wiley   +1 more source

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