Results 221 to 230 of about 587,595 (299)

Playing with Numbers: The Social and Behavioural Impacts of Using a Card Game to Teach Business Metrics. [PDF]

Behav Sci (Basel)
Smith R, Conway E.
europepmc   +1 more source

CD74 Blockade Disrupts Endothelial Migrasome Signaling to Prevent Inflammatory Macrophage Differentiation and Inhibit Atherosclerotic Progression

Advanced Science, EarlyView.
Migrasomes play a crucial role in endothelial‐immune interactions in atherosclerosis. This study identifies migrasomes as amplifiers in the inflammatory cascade, driving immune‐metabolic reprogramming via “migrasome‐APP‐CD74” signaling. Blocking CD74 disrupts migrasome‐mediated signaling, attenuating atherosclerosis progression.
Kangnan Zhang, Jiong Chen, Zhenhua Zhu, Hong Hu, Qinghui Zhang, Rongrong Jia, Na Wang, Shihao Xiang, Yong Zhou, Yuehong Wang, Ling Xu   +10 more
wiley   +1 more source

Playing repeated games with large language models. [PDF]

Nat Hum Behav
Akata E, Schulz L, Coda-Forno J, Oh SJ, Bethge M, Schulz E.   +5 more
europepmc   +1 more source

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

Advanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu, Han Li, Shuang‐feng Zi, Ying Tang, Na Liu, Ke‐xin Li, Shi‐ke Geng, Hui‐qing Lu, Zhi‐kang Xie, Xin‐yi Xu, Yi‐ting Wei, Li‐xin Wang, Tao Liu, Jie Chao, Yi Yang, Hai‐bo Qiu, Wei Huang, Ling Liu   +17 more
wiley   +1 more source

Advancements and challenges in methodological approaches for game-based health interventions: a scoping review. [PDF]

Front Digit Health
Glass S, Galati A.
europepmc   +1 more source

Hexokinase‐2 as a Therapeutic Target: Alleviating Herpes Simplex Keratitis Through Metabolic Reprogramming

Advanced Science, EarlyView.
Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang, Yining Sun, Xintong Yu, Ruoqi Wang, Yuting Zhang, Jinjie Yu, Shuang Xie, Yujia Cai, Yuhong Luo, Wei Chen   +9 more
wiley   +1 more source

A game study on the evolution of carbon emission reduction behavior of Chinese power enterprises. [PDF]

Sci Rep
Liu Y, Gao C, Liu J.
europepmc   +1 more source

Prompting Interfacial Elastic Instability for Effective and Durable Icephobic Surfaces

Advanced Science, EarlyView.
To address the inherent trade‐off between icephobicity and the mechanical strength of icephobic materials, a new icephobic material design strategy is proposed by integrating fibrous construction frameworks and icephobic polymer. The structure prompts interfacial elastic instability and the subsequent undulatory interfacial stress at ice/solid ...
Xinyu Fan, Jingtong Li, Deyu Yang, Jie Fei, Hejun Li, Xianghui Hou   +5 more
wiley   +1 more source

Personalizing mobile applications for health based on user profiles: A preference matrix from a scoping review. [PDF]

PLOS Digit Health
Gosetto L, Falquet G, Ehrler F.
europepmc   +1 more source

A Novel nor@DHB Matrix for Direct Microbial Analysis in Lung Cancer Tissues

Advanced Science, EarlyView.
Integrated matrix‐assisted laser desorption/ionization mass spectrometry workflow quantifies intratumoral microbes in lung cancer through lipopolysaccharide/lipid A extraction from biopsies. The novel ionic matrix called norharmane conjugated to 2,5‐dihydroxybenzoic acid enhances lipid A ionization, enabling direct detection of bacterial genera ...
Liang Shan, Xin Xu, Lin Huang, Dan Li, Yiran Deng, Xiangfei Xue, Susu Guo, Yiman Huang, Xiao Zhang, Yongchun Yu, Lifang Ma, Kun Qian, Jiayi Wang   +12 more
wiley   +1 more source