Results 221 to 230 of about 334,200 (306)

Inconsistent Bodily Feedback? Interoceptive Sensibility Affects Internet Gaming Disorder in Emerging Adults. [PDF]

Behav Sci (Basel)
Lv Z, Li C, Zhang J, He J.
europepmc   +1 more source

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

An adaptive dynamics framework for microbial ecology and evolution. [PDF]

Sci Rep
Karlsson CJ, Gerlee P, Rowlett J.
europepmc   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Picking strategies in games of cooperation. [PDF]

Proc Natl Acad Sci U S A
García J, Traulsen A.
europepmc   +1 more source

Inhaling Eugenol Inhibits NAFLD by Activating the Hepatic Ectopic Olfactory Receptor Olfr544 and Modulating the Gut Microbiota

Advanced Science, EarlyView.
Inhalable eugenol (EUG) from clove oil attenuates NAFLD by activating hepatic olfactory receptor Olfr544, triggering cAMP/PKA/CREB signaling to enhance lipolysis/oxidation. EUG concurrently restores gut microbiota, enriching probiotics (L. reuteri XR23/L. johnsonii XR25) and metabolites (IPA/5‐HIAA) that suppress lipogenesis.
Xiao‐Ran Wang, Zhan‐Zhan Li, Shu‐Ding Sun, Ya‐Gang Song, Jin‐Xin Miao, Xiang‐Xiang Wu, Yong‐Li Han, Xiao‐Lei Zhang, Wen‐Jing Chen, Qing‐Hua Wang, Yu Zhang, Yiping Fu, Yu‐ting Liu, Lin‐yan Lang, Wen‐Xia Zhao, Ming‐San Miao   +15 more
wiley   +1 more source

Investigating the effects of single-dose intranasal testosterone on economic preferences in a large randomized trial of men. [PDF]

Proc Natl Acad Sci U S A
Dreber A, Johannesson M, Nave G, L Apicella C, Geniole SN, Imai T, L Knight E, Manfredi D, Mehta PH, Proietti V, Stanton SJ, Zeltikova A, R Luberti F, Ortiz T, Carré JM.   +14 more
europepmc   +1 more source

Acceptability, Usability, and Effectiveness of a Music Video Game for Pain Management: A Crossover Study. [PDF]

Healthcare (Basel)
Esteban-Sopeña J, Bravo-Aparicio J, Trillo-Charlín I, Roldán-Ruiz A, Beltran-Alacreu H, García-Magro N.   +5 more
europepmc   +1 more source

Heterogeneity, reinforcement learning, and chaos in population games. [PDF]

Proc Natl Acad Sci U S A
Bielawski J, Chotibut T, Falniowski F, Misiurewicz M, Piliouras G.   +4 more
europepmc   +1 more source

The Influence of Perceived Fairness on Trust in Human-Computer Interaction. [PDF]

Int J Psychol
Chen R, Jin Y, Yu L, Tempel T, Li P, Zhang S, Li A, He W.   +7 more
europepmc   +1 more source