Results 71 to 80 of about 617,560 (302)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Games and gamers: the influence of participating players on the process and outcome of regional spatial energy games

Energy, Sustainability and Society
Background One major question of climate and energy policy is how to act under conditions of great uncertainty. This contribution relates to the literature that studies how various actors draft regional energy scenarios and pathways in so-called serious ...
Hartmut Dumke, Pia Nabielek
doaj   +1 more source

Integrating video-game music into Electone pedagogy in China: investigating learning process and outcomes

Frontiers in Education
Available studies have examined game’s impact on music education from the learning outcome perspective. This sequential mixed-method design attempted to explore the impact of video-game music as Electone pedagogy on students’ learning process and outcome.
Jiachen Wei, Saifon Songsiengchai, Yaoping Liu, Tassanee Laknapichonchat   +3 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Strategic delegation in a sequential model with multiple stages

, 2012
We analyze strategic delegation in a Stackelberg model with an arbitrary number, n, of firms. We show that the n-1 last movers delegate their production decisions to managers whereas the first mover does not. Equilibrium incentive rates are increasing in
Fershtman C., GIORGOS STAMATOPOULOS, PARASKEVAS V. LEKEAS, Scalera D.   +3 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

To negotiate or to game theorize: Negociation vs. game theory outcomes for water allocation problems in the Kat Basin, South Africa [PDF]

, 2006
Common property resource disputes are increasing, due to increase in competition and deterioration of quality. Cooperative arrangements have long been in the center of public interest regarding the mechanisms used by communities that share them. Two main approaches have been applied separately, namely negotiation approaches and cooperative game theory.
Dinar, Ariel, Farolfi, Stefano, Patrone, Fioravante, Rowntree, Kate   +3 more
openaire   +1 more source

THE RELATIONSHIP BETWEEN THEORY AND PRACTICE LEARNING ON SHOOTING LEARNING OUTCOMES IN FUTSAL GAMES

Gladi : Jurnal Ilmu Keolahragaan
Education is something that must be embedded in humans. One way to obtain education is through school. Schools are institutions that provide various types of education such as knowledge, character, morals and so on. Physical Education is one of the education to improve the quality of humans who have noble character, are intelligent and physically and ...
Hidayatullah, Alfian, Yono, Topo, Difitriyani, Herma   +2 more
openaire   +2 more sources

The Naming Game in Social Networks: Community Formation and Consensus Engineering

, 2010
We study the dynamics of the Naming Game [Baronchelli et al., (2006) J. Stat. Mech.: Theory Exp. P06014] in empirical social networks. This stylized agent-based model captures essential features of agreement dynamics in a network of autonomous agents ...
A Bray, B Kozma, B Kozma, Boleslaw K. Szymanski, C Castellano, C Cattuto, D Challet, D Vinkovic, DJ Watts, E Ben-Naim, F Wu, G Deffuant, G Palla, G Palla, G. Korniss, I Benczik, J Dall, J Lorenz, J Moody, J Reichardt, J Scott, J Zhang, JM Epstein, JM Kumpula, JP Onnela, K Sznajd-Weron, KI Mazzitello, L Dall’Asta, L Dall’Asta, M Blatt, M Girvan, M Lim, M Penrose, M San Miguel, MC Gonzáles, MEJ Newman, MEJ Newman, MEJ Newman, Q Lu, Qiming Lu, R Axelrod, R Hegselmann, R Meester, S Fortunato, S Golder, SN Durlauf, T Antal, TC Schelling, V Sood, WS Jung, WX Wang   +50 more
core   +2 more sources

Cognitive Status in People With Epilepsy in the Republic of Guinea: A Prospective, Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective People with epilepsy (PWE) may experience cognitive deficits but fail to undergo formal evaluation. This study compares cognitive status between PWE and healthy controls in the West African Republic of Guinea. Methods A cross‐sectional, case–control study was conducted in sequential recruitment phases (July 2024–July 2025) at Ignace ...
Maya L. Mastick, Cheick O. Soumah, Malé Doré, Oumar Mara, Desiré Neldje, Fodé A. Cissé, Toure M. Lamine, Aminata Diallo, Seungwon Lee, Siddharth Satish, Alexander J. X. Chen, Alice Liu, Nomin Enkhtsetseg, Farrah J. Mateen, The Guinea Epilepsy Project   +14 more
wiley   +1 more source