Results 151 to 160 of about 16,988,510 (382)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Real-world association between systemic corticosteroid exposure and complications in US patients with severe asthma

open access: yesAllergy, Asthma & Clinical Immunology
Background Systemic corticosteroid (SCS) use remains widespread among patients with severe asthma, despite associated complications. Objective Evaluate the association between cumulative SCS exposure and SCS-related complications in severe asthma ...
Thomas B Casale   +7 more
doaj   +1 more source

Ataxia-telangiectasia: immunologic profile and clinical outcome [PDF]

open access: gold, 2015
Clarissa De Lima Honório Dumas   +5 more
openalex   +1 more source

Comorbidities Burden and Implementation of the Treat–to–Target Strategy in Predicting Real-World Patient Outcomes in Spondyloarthritides

open access: diamond, 2023
Irini Flouri   +9 more
openalex   +1 more source

Semaglutide and Cardiovascular Outcomes in Patients with Type 2 Diabetes.

open access: yesNew England Journal of Medicine, 2016
S. Marso   +14 more
semanticscholar   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

open access: yesNew England Journal of Medicine, 2016
M. Fischereder, U. Schönermarck
semanticscholar   +1 more source

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