Results 161 to 170 of about 4,586,853 (323)

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

Molecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock, Lina Benzien, Sandra Lange, Maja Huehns, Alexandra Runge, Catrin Roolf, Anett Sekora, Gudrun Knuebel, Hugo Murua Escobar, Christian Junghanss, Anna Richter   +10 more
wiley   +1 more source

Easing the Transfer of Students from College to University Programs: How Can Learning Outcomes Help?

, 1969
Irene Carter, James P. Coyle, Donald R. Leslie   +2 more
openalex   +2 more sources

EFFECTS OF INSULIN ON PLACENTAL, FETAL AND MATERNAL OUTCOMES IN GESTATIONAL DIABETES MELLITUS [PDF]

, 1969
Rabia Arshad, Dr Nasim Karim, Dr Jehan Ara Hasan   +2 more
openalex   +1 more source

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

Molecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar, Shima Shahbaz, Anthea C. Peters, Spencer B. Gibson, Shokrollah Elahi   +4 more
wiley   +1 more source

Comparison of Online Peer-Assisted Learning and Faculty-Led Teaching for Short Answer Questions. [PDF]

Clin Teach
Samra GS, Gaddu K, Hee JRWS, Brahmbhatt K, Bowrey D, Seabrook M.   +5 more
europepmc   +1 more source

Frequency and outcome of treatment in polycystic ovaries related infertility [PDF]

, 1969
Farzana Rizwan
openalex   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Evolution of the Florida Pediatric Bone Marrow Transplant and Cell Therapy Consortium (FPBCC): A Statewide Initiative Toward Improving Transplant Outcomes. [PDF]

Pediatr Transplant
Alperstein W, Lee JJ, Chellapandian D, Booth N, Galvez-Silva J, Joyce M, Milner J, Castillo P, Kashif R, Dalal M, Ligon J, Crawford D, Alicea Marrero MM, Peters J, Horn B, Dela Ziga E.   +15 more
europepmc   +1 more source

Can living donor liver transplantation offer similar outcomes to deceased donor liver transplantation using expanded selection criteria for hepatocellular carcinoma?

, 1969
Liping Chen, Chuan Li, Tian-Fu Wen, Lu-Nan Yan, Bo Li, Jiayin Yang   +5 more
openalex   +1 more source

Outcome studies [PDF]

Developmental Medicine & Child Neurology, 1999
openaire   +2 more sources