Results 211 to 220 of about 4,586,853 (323)

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

Radical cystectomy for bladder cancer in Sub-Saharan Africa: techniques, challenges, and survival outcomes: a comprehensive review. [PDF]

BMC Surg
Nhungo CJ, Nyongole OV, Mkony CA.
europepmc   +1 more source

Relation between smallpox vaccination and outcome of pregnancy.

, 1968
Lauri Saxén, K Cantell, M Hakama
openalex   +2 more sources

Integration of intention and outcome in moral judgment [PDF]

, 1976
J. Clark Lane, Norman H. Anderson
openalex   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

Molecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh, Amelia Martinez Villarreal, Philippe Lefrançois, Jennifer Gantchev, Sriraam Sivachandran, Samy Abou Setah, Ivan V. Litvinov   +6 more
wiley   +1 more source

Birmingham Hip Resurfacing: a retrospective cohort study of clinical, biochemical, and radiological outcomes in a non-designer centre at minimum 15 years' follow-up. [PDF]

Bone Jt Open
Davey MS, Farrell C, Kilkenny C, Medlar C, McGoldrick NP, Quinlan JF.   +5 more
europepmc   +1 more source

SHORT TERM OUTCOME OF LAPAROSCOPIC VENTRAL RECTOPEXY FOR RECTAL PROLAPSE

, 1969
Muhammad Naeem
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source

International consensus-based core outcome set for airway management clinical trials and observational studies: the Airway Terminology and Outcome Measures (ATOM) protocol. [PDF]

BMJ Open
Hansel J, Fuchs A, Radcliffe G, Sotiriou A, Rivett K, Bohnenblust V, Grimes R, Fally M, Greif R, Cook TM, El Boghdadly K, Airway Terminology and Outcome Measures (ATOM) Group.   +11 more
europepmc   +1 more source

Medical care of school children: factors influencing outcome of referral from a school health program.

, 1967
J G Cauffman, E. Petersen, J A Emrick
openalex   +1 more source