Results 271 to 280 of about 15,903,898 (384)
Development of a core patient-centred outcome set for adults living with obesity: a modified delphi-based international consensus. [PDF]
EClinicalMedicineMekonnen T, Staniford L, Connell S, Das-Gupta Z, DeSilva U, Saoud Y, Miller I, Mohan M, Nienhuijs S, Poddar M, Deshmukh VC, Conradie-Smit M, Teoh SH, Sockalingam S, Huvinen E, Sbraccia P, Liem R, Vallis M, Clare K, Zvenyach T, Coulman K, Ackermann MA, Vázquez-Velázquez V, Contreras YP, Vidal J, Urudinachi A, Tejeda-Muñoz MF, Patton I, Samuels TA, Gabriel Salmon Leguede ME, Rigas G, Salas XR, Crotty M, Halpern B, Bessesen D, Pizzi L, Al Hajeri OM, Sharma AM. +37 moreeuropepmc +1 more sourceTherapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim +18 morewiley +1 more sourceCorrection: COMET (Composite Outcomes of Mesh vs suture Techniques for prolapse repair)- Protocol for a single blind randomized controlled multicenter trial testing surgical innovation in female pelvic surgery. [PDF]
PLoS OneRoa L, Larouche M, Hyakutake M, Brennand EA, Malabarey O, Koenig N, Lee T, Singer J, Zhang W, Brotto LA, Geoffrion R. +10 moreeuropepmc +1 more sourceEffects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy.
New England Journal of Medicine, 2001 B. Brenner, M. Cooper, D. Zeeuw, W. Keane, W. Mitch, H. Parving, G. Remuzzi, S. Snapinn, Zhonxin Zhang, S. Shahinfar +9 moresemanticscholar +1 more sourceUnraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández +12 morewiley +1 more sourceInterstitial Thermal Therapy in Mesial Temporal Lobe Epilepsy.
JAMA NeurolLandazuri P, Cheng JJ, Leuthardt E, Kim AH, Southwell DG, Fecci PE, Neimat J, Sun D, Lega B, Panov F, Chiang V, Abel T, Ben-Haim S, Piccioni DE, Shih JJ, Palys V, Rodriguez A, Bandt SK, Petronio J, Lacroix M, Baumgartner J. +20 moreeuropepmc +1 more sourceClinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy.
New England Journal of Medicine, 2015 C. Templin, J. Ghadri, J. Diekmann, L. C. Napp, D. Bataiosu, M. Jaguszewski, V. L. Cammann, A. Sarcon, V. Geyer, C. Neumann, B. Seifert, J. Hellermann, Moritz Schwyzer, Katharina Eisenhardt, J. Jenewein, J. Franke, H. Katus, C. Burgdorf, H. Schunkert, C. Moeller, H. Thiele, J. Bauersachs, C. Tschöpe, H. Schultheiss, C. Laney, Lawrence Rajan, G. Michels, R. Pfister, C. Ukena, M. Böhm, R. Erbel, A. Cuneo, K. Kuck, C. Jacobshagen, G. Hasenfuss, M. Karakas, W. Koenig, W. Rottbauer, S. Said, R. Braun-Dullaeus, F. Cuculi, A. Banning, T. Fischer, T. Vasankari, K. Airaksinen, M. Fijałkowski, A. Rynkiewicz, M. Pawlak, G. Opolski, R. Dworakowski, P. MacCarthy, C. Kaiser, S. Osswald, L. Galiuto, F. Crea, W. Dichtl, W. Franz, K. Empen, S. Felix, C. Delmas, O. Lairez, P. Erne, Jeroen J. Bax, I. Ford, F. Ruschitzka, A. Prasad, T. Lüscher +66 moresemanticscholar +1 more source