Results 321 to 330 of about 15,903,898 (384)

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

Surgical outcomes of minimally invasive microscopic debridement in thoracolumbar pyogenic spondylodiscitis. [PDF]

Sci Rep
Park SM, Kwon O, Park J, Ham DW, Kim HJ, Yeom JS.   +5 more
europepmc   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

Virtual-Based Prenatal Care Methods and Their Reported Outcomes-A Scoping Review. [PDF]

Health Sci Rep
Sabetrohani H, Koohpayehzadeh J, Sheikhtaheri A, Goli S, Abhari MB, Keramat A.   +5 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

What measures have been used to explore the outcomes of family members of critically ill patients: a scoping review. [PDF]

Intensive Care Med
Brown C, Hartley P, Forsyth F, Boehm LM, Martin G, Kuhn I, Pattison N, Connolly B, Lone N, Danesh V, McPeake J.   +10 more
europepmc   +1 more source

Socioeconomic Area Deprivation is Related to Poorer Patient-Reported Outcomes Following Autologous Chondrocyte Implantation (ACI). [PDF]

Cartilage
Ismael ST, McCarthy HS, Wright K, Williams M, Barnett A, Gallacher P, Jermin P, Roberts S, Kuiper JH.   +8 more
europepmc   +1 more source

Functional Outcomes of Displaced Midshaft Clavicular Fractures Treated with Precontoured Locked Plates: A Prospective Study. [PDF]

F1000Res
Al-Moaish AA, Algabarty JA, Mughallas A, Alhamzi AM, Soliaman M, Hutaif M, Abdulmoghni M, Almahdi AH, Jowah HM.   +8 more
europepmc   +1 more source

The impact of shortening shifts of physicians during their residency on patients and physicians : A systematic review and meta-analysis. [PDF]

Isr J Health Policy Res
Daitch V, Poran I, Leibovici L.
europepmc   +1 more source