Dwarf Galaxies in Clusters as Probes of Galaxy Formation and Dark Matter
We present the results of a Hubble Space Telescope (HST) ACS and WFPC2 study of dwarf galaxies in the nearby Perseus Cluster, down to M_V = -12, spanning the core and outer regions of this cluster.
C.J. Conselice +13 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
A novel bipartite centrosome coordinates the apicomplexan cell cycle.
Apicomplexan parasites can change fundamental features of cell division during their life cycles, suspending cytokinesis when needed and changing proliferative scale in different hosts and tissues.
Elena S Suvorova +3 more
doaj +1 more source
Crystal structure of Legionella DotD: insights into the relationship between type IVB and type II/III secretion systems. [PDF]
The Dot/Icm type IVB secretion system (T4BSS) is a pivotal determinant of Legionella pneumophila pathogenesis. L. pneumophila translocate more than 100 effector proteins into host cytoplasm using Dot/Icm T4BSS, modulating host cellular functions to ...
Noboru Nakano +4 more
doaj +1 more source
Unveiling the detailed density and velocity structures of the protostellar core B335
We present an observational study of the protostellar core B335 harboring a low-mass Class 0 source. The observations of the H13CO+(J=1-0) line emission were carried out using the Nobeyama 45 m telescope and Nobeyama Millimeter Array.
Kamazaki, Takeshi +4 more
core +1 more source
The first principles calculation of transport coefficients [PDF]
We demonstrate the practical feasibility of calculating transport coefficients such as the viscosity of liquids completely from first principles using the Green-Kubo relations.
Alfe`, Dario, Gillan, Michael J.
core +2 more sources
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Effects of a radially varying electrical conductivity on 3D numerical dynamos
The transition from liquid metal to silicate rock in the cores of the terrestrial planets is likely to be accompanied by a gradient in the composition of the outer core liquid.
Gomez-Perez, Natalia +2 more
core +1 more source
Carbon Partitioning Between the Earth's Inner and Outer Core [PDF]
AbstractKnowledge of the abundance and distribution of light elements in the core is fundamental to the understanding of the Earth and other planetary systems. Recent studies (Li et al., 2018; Mashino et al., 2019) suggest the particular importance of carbon for explaining core properties, yet knowledge of carbon partitioning between the outer and ...
Li Y., Vocadlo L., Alfe D., Brodholt J.
openaire +3 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source

