Results 51 to 60 of about 143,077 (265)

A Modular Liver–Microbial Microfluidic Platform to Evaluate Therapeutic and Adverse Effects of Microbial Metabolites

Advanced Healthcare Materials, EarlyView.
This study introduces a modular microfluidic platform that connects liver cells with live microbes to mimic key aspects of the gut–liver interaction in steatosis. Using this system, both microbial metabolites and live bacteria significantly reduced fat accumulation in liver cells, but live microbes triggered inflammation and broader metabolic changes ...
Hsih‐Yin Tan, In Young Hwang, Nanthini Jayabalan, Hui Ling Lee, Louis Jun Ye Ong, Chwee Teck Lim, Matthew Wook Chang, Yi‐Chin Toh   +7 more
wiley   +1 more source

Testing hypotheses of the cause of peripheral thinning of the Greenland Ice Sheet: is land-terminating ice thinning at anomalously high rates? [PDF]

The Cryosphere, 2008
Recent observations have shown that the periphery of the Greenland ice sheet (GrIS) is thinning rapidly and that this thinning is greatest around marine-terminating outlet glaciers. Several theories have been proposed which provide a link between climate
A. Sole, T. Payne, J. Bamber, P. Nienow, W. Krabill   +4 more
doaj  

Gastric Outlet Obstruction

JAMA Surgery, 2016
A 72-year-old woman presented with a 6-month history of a dull, epigastric pain, 10-kg weight loss (from 52 kg to 42 kg), and a 6- to 8-week history of nausea and vomiting. Physical examination showed no notable abnormalities. Blood test results revealed anemia (hemoglobin 9.8 g/dL [to convert to grams per liter, multiply by 10]) but were otherwise ...
de Meijer, Vincent E., van Eijck, Casper H. J., Koerkamp, Bas Groot   +2 more
openaire   +2 more sources

A 3D‐Printed Vascular‐Like Perfusion Tumor‐on‐a‐Chip Recapitulates High‐Grade Breast Cancer With in Vivo‐Relevant Drug Resistance

Advanced Healthcare Materials, EarlyView.
A high‐resolution 3D‐printed tumor‐on‐a‐chip platform sustains breast cancer tissues at in vivo–like cell densities through vascular‐like perfusion. This engineered system recapitulates grade‐dependent molecular features and exhibits drug‐resistance profiles that uniquely align with clinically relevant Cmax values.
Geonhui Lee, Bingjie Sun, Nicholas X. Fang, Chunguang Xia   +3 more
wiley   +1 more source

Unusual case of absent right-sided atrioventricular connection with double outlet left atrium with parachute left-sided atrioventricular valve leaflets

IHJ Cardiovascular Case Reports, 2018
Double outlet left atrium with right atrial outlet atresia is reported in literature as a rare entity. We report an extremely unusual case of a 2 year old child with double outlet left atrium, right atrial outlet atresia along with parachute left sided ...
Gaurav Agrawal, Amit Kumar Chaurasia
doaj   +1 more source

Portable Molecularly Imprinted Polymer Sensor for Rapid Swab‐Based Detection of Norovirus

Advanced Healthcare Materials, EarlyView.
This work reports a rapid, portable smartphone‐based sensor capable of detecting four norovirus genotypes from swab samples within 15 min. Sensor selectivity was validated through evaluation against four common live viruses. The swab‐based sampling process enabled simple sample preparation combined with the compact detection system, supporting use of ...
Amy Dann, Pankaj Singla, Minji Kim, Sloane Stoufer, Clare Thomas, Robert D. Crapnell, Craig E. Banks, Jake McClements, Shayan Seyedin, Mark Geoghegan, Samuel T. Jones, Christopher F. Blanford, Matthew D. Moore, Marloes Peeters   +13 more
wiley   +1 more source

Tomographic Printing in a Chip: A Versatile Platform for Biomimetic 3D Organ‐on‐Chip

Advanced Healthcare Materials, EarlyView.
A novel light‐based bioprinting approach, TVAM‐in‐a‐chip, enables rapid, contactless fabrication of biomimetic 3D organ‐on‐chip devices directly within preassembled microfluidic platforms. This strategy supports diverse materials, including cell‐laden resins, and eliminates post‐assembly steps.
Riccardo Rizzo, Viola Sgarminato, Felix Wechsler, Christophe Moser   +3 more
wiley   +1 more source

Pyloric Stenosis-like Gastric Outlet Obstruction Following Gastric Bypass: A Case Report

The Annals of African Surgery
This case report describes a rare instance of hypertrophic pyloric stenosis (HPS) presenting after gastric bypass surgery in an adult patient. The patient exhibited symptoms of gastric outlet obstruction, including persistent vomiting and weight loss ...
Hussam Trabulsi, Tala Muassess, Yousif El Taye, Dina Trabulsi   +3 more
doaj   +1 more source

Mechanotransduction of Magnetically Applied Forces Leads to Mechanical Stiffening of Platelet‐Rich Plugs

Advanced Healthcare Materials, EarlyView.
A microfluidic device with magnetic microposts was used to assess platelet mechanobiology. The oscillatory actuation of posts with embedded iron particles was dampened by the dynamic stiffening of the platelet‐rich plugs. This stiffening process increased with applied load, but inhibiting platelet activation (ASA) or myosin contractility (blebbistatin)
Nikita Taparia, Ava M. Obenaus, Yoeur‐Man T. Mach, Nakul Sridhar, Nathan J. Sniadecki   +4 more
wiley   +1 more source

Mixed‐Metal Promotion in a Manganese‐Molybdenum Oxynitride as Catalyst to Integrate C─C and C─N Coupling Reactions for the Direct Synthesis of Acetonitrile from Syngas and Ammonia

Advanced Materials, EarlyView.
Transition metal oxy/carbo‐nitrides show great promise as catalysts for sustainable processes. A Mn‐Mo mixed‐metal oxynitride attains remarkable performance for the direct synthesis of acetonitrile, an important commodity chemical, via sequential C─N and C─C coupling from syngas (C1) and ammonia (N1) feedstocks.
M. Elena Martínez‐Monje, Wilson Henao, Tania Rodenas, Patricia Concepción, Virginia Pérez Dieste, Alexander Missyul, Giovanni Agostini, Gonzalo Prieto   +7 more
wiley   +1 more source