Results 181 to 190 of about 963,417 (295)

Uniform processing and analysis of IGVF massively parallel reporter assay data with MPRAsnakeflow. [PDF]

open access: yesGenome Res
Rosen JD   +12 more
europepmc   +1 more source

Outlier removal algorithm in pose transformation

open access: yes
In SLAM algorithms, each keyframe is typically treated as a node, and sensor data is used to compute the pose transformations (rotation matrix R and translation vector t) between different keyframes. These pose transformations can be viewed as edges connecting the nodes, allowing the relationships between the nodes to be represented in the form of a ...
openaire   +2 more sources

Assessing Strengths and Limitations of Magnetoencephalography Source Imaging With Intracerebral EEG

open access: yesAdvanced Science, EarlyView.
Simultaneous MEG and stereotactic EEG (SEEG) recordings provide a direct validation framework for MEG source imaging in focal epilepsy. Virtual SEEG signals derived from MEG reconstructions reveal significant agreement with intracranial measures of spike localization, resting‐state oscillations, and functional connectivity, while also identifying ...
Jawata Afnan   +10 more
wiley   +1 more source

A Bright Ratiometric Dipyrene Probe for Functional Imaging of Condensate Microenvironments in Living Cells

open access: yesAdvanced Science, EarlyView.
Ratiometric dipyrene imaging resolves monomer (M) and excimer (E) channels and computes pixel‐wise E/M maps within biomolecular condensates, yielding physicochemical fingerprints shaped by coupled polarity‐related solvation and microviscosity. These spatial fingerprints enable quantitative phenotyping of cellular states, exemplified by separation of ...
Koki Matsumoto   +20 more
wiley   +1 more source

Drawing a line in the sand: impact of analytical choices on anti-drug antibody cut-points and testing outcomes. [PDF]

open access: yesBioanalysis
Weiner JA   +7 more
europepmc   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

open access: yesAdvanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker   +11 more
wiley   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

open access: yesAdvanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai   +9 more
wiley   +1 more source

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