Results 11 to 20 of about 539,030 (309)

Quality of Life in Asthmatic Patients [PDF]

حیات, 2007
Background & Aim: Asthma, as a chronic respiratory disease, is a major health problem worldwide. The quality of life of asthmatic patients is affected by long-term treatment and continuous episodes of asthmatic attacks. The aim of this study is to assess
SH Pedram Razi, SH  Bassampour, A  Kazemnejad   +2 more
doaj   +1 more source

Strategies for Isolating and Propagating Circulating Tumor Cells in Men with Metastatic Prostate Cancer

Diagnostics, 2022
Selecting a well-suited method for isolating/characterizing circulating tumor cells (CTCs) is challenging. Evaluating sensitive and specific markers for prostate cancer (PCa)-specific CTC identification and analysis is crucial.
Gerit Theil, Joanna Bialek, Christine Weiß, Felix Lindner, Paolo Fornara   +4 more
doaj   +1 more source

Differential Expression of the Androgen Receptor, Splice Variants and Relaxin 2 in Renal Cancer

Life, 2021
Background: The role of the androgen receptor (AR) in renal cell carcinoma (RCC) is unclear. We aimed to analyze the expression of AR and its splice variants (SVs) and their correlation with relaxin 2 (RLN2) and cytokines in RCC. Methods: We investigated
Joanna Bialek, Maria Piwonka, Felix Kawan, Paolo Fornara, Gerit Theil   +4 more
doaj   +1 more source

Relative versus absolute RNA quantification: a comparative analysis based on the example of endothelial expression of vasoactive receptors

Biological Procedures Online, 2021
Background In the present study, two distinct PCR methods were used for the quantification of genetic material and their results were compared: real-time-PCR (qPCR; relative quantification) and droplet digital PCR (ddPCR; absolute quantification).
Kevin Kuhlmann, Melanie Cieselski, Julia Schumann   +2 more
doaj   +1 more source

Predictors of failed attendances in a multi-specialty outpatient centre using electronic databases. [PDF]

, 2005
BACKGROUND: Failure to keep outpatient medical appointments results in inefficiencies and costs. The objective of this study is to show the factors in an existing electronic database that affect failed appointments and to develop a predictive probability
Arul Earnest, AS Yassin, AV Simmons, B Pal, Bala Krishnan, CG Moore, D Hermoni, D Thomas, DC Gruzd, G Sanders, Gatrad, GL Oppenhiem, JWY Chung, LA Adams, Mark I Chen, MP Cosgrove, P Patel, RA Deyo, S Frankel, SA al-Shammari, SB Cashman, SJ Griffin, Stata Corp, Vernon J Lee, W Dickey, W Hamilton, WM Barron, WM Macharia   +27 more
core   +3 more sources

Self‐reported quality of life in symptomatic and asymptomatic women with X‐linked adrenoleukodystrophy

Brain and Behavior, 2023
Background Up to 80% of women with X‐linked adrenoleukodystrophy (X‐ALD) develop symptoms of myelopathy and peripheral neuropathy during their lifetime. The study's objective was to compare symptomatic versus asymptomatic women with X‐ALD regarding their
Lisa Schäfer, Hannes Roicke, Christa‐Caroline Bergner, Wolfgang Köhler   +3 more
doaj   +1 more source

Fracture clinic redesign reduces the cost of outpatient orthopaedic trauma care [PDF]

, 2016
Objectives: “Virtual fracture clinics” have been reported as a safe and effective alternative to the traditional fracture clinic. Robust protocols are used to identify cases that do not require further review, with the remainder triaged to the most ...
Anderson, G., Jenkins, P.J., Morton, A., Rymaszewski, L.A., Van Der Meer, R.B.   +4 more
core   +1 more source

Home sampling for sexually transmitted infections and HIV in men who have sex with men: a prospective observational study [PDF]

, 2015
To determine uptake of home sampling kit (HSK) for STI/HIV compared to clinic-based testing, whether the availability of HSK would increase STI testing rates amongst HIV infected MSM, and those attending a community-based HIV testing clinic compared to ...
Carrie Llewellyn, Catherine Ison, Daniel Richardson, Garth Singleton, Helen Smith, John V Parry, Martin Fisher, Nicky Perry, null null, Sarah Alexander, Sonali Wayal   +10 more
core   +6 more sources

Potential Use of CTCs as Biomarkers in Renal Cancer Patients

Life, 2022
We demonstrated that the CellCollector is an appropriate tool for detecting CTCs in RCC patients. We examined EpCAM and MUC1 expression levels in RCC tissues and cell lines and analyzed the detection rate of CTCs in blood samples ex vivo using an anti ...
Joanna Bialek, Andreas Wencker, Felix Kawan, Stefan Yankulov, Paolo Fornara, Gerit Theil   +5 more
doaj   +1 more source

Hypomorphic Mutations in the BCR Signalosome Lead to Selective Immunoglobulin M Deficiency and Impaired B-cell Homeostasis

Frontiers in Immunology, 2018
B cell activation via the B cell receptor (BCR) signalosome involves participation of signaling molecules such as BTK and BLNK. Genetic defects in these molecules are known to impair B cell differentiation and subsequently lead to agammaglobulinemia ...
Christoph B. Geier, Kai M. T. Sauerwein, Alexander Leiss-Piller, Isabella Zmek, Michael B. Fischer, Michael B. Fischer, Martha M. Eibl, Martha M. Eibl, Hermann M. Wolf, Hermann M. Wolf   +9 more
doaj   +1 more source