Results 81 to 90 of about 921,934 (330)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Convex hulls of spheres and convex hulls of convex polytopes lying on parallel hyperplanes [PDF]

open access: yes, 2011
Given a set $\Sigma$ of spheres in $\mathbb{E}^d$, with $d\ge{}3$ and $d$ odd, having a fixed number of $m$ distinct radii $\rho_1,\rho_2,...,\rho_m$, we show that the worst-case combinatorial complexity of the convex hull $CH_d(\Sigma)$ of $\Sigma$ is $\
Karavelas, Menelaos I., Tzanaki, Eleni
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Hacking Smart Machines with Smarter Ones: How to Extract Meaningful Data from Machine Learning Classifiers [PDF]

open access: yes, 2013
Machine Learning (ML) algorithms are used to train computers to perform a variety of complex tasks and improve with experience. Computers learn how to recognize patterns, make unintended decisions, or react to a dynamic environment.
Ateniese, Giuseppe   +5 more
core  

Secure Multi-Party Computation Based Privacy Preserving Extreme Learning Machine Algorithm Over Vertically Distributed Data

open access: yes, 2015
Especially in the Big Data era, the usage of different classification methods is increasing day by day. The success of these classification methods depends on the effectiveness of learning methods.
Çatak, Ferhat Özgür
core   +1 more source

Computing Non-Dominated Flexible Skylines in Vertically Distributed Datasets with No Random Access

open access: yesData
In today’s data-driven world, algorithms operating with vertically distributed datasets are crucial due to the increasing prevalence of large-scale, decentralized data storage.
Davide Martinenghi
doaj   +1 more source

Time-of-Travel Methods for Measuring Optical Flow on Board a Micro Flying Robot

open access: yesSensors, 2017
For use in autonomous micro air vehicles, visual sensors must not only be small, lightweight and insensitive to light variations; on-board autopilots also require fast and accurate optical flow measurements over a wide range of speeds.
Erik Vanhoutte   +4 more
doaj   +1 more source

A CNN-Based Wearable System for Driver Drowsiness Detection

open access: yesSensors, 2023
Drowsiness poses a serious challenge to road safety and various in-cabin sensing technologies have been experimented with to monitor driver alertness. Cameras offer a convenient means for contactless sensing, but they may violate user privacy and require
Yongkai Li   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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