Results 121 to 130 of about 3,443,578 (303)
A CMOS class-AB transconductance amplifier for switched-capacitor applications [PDF]
A CMOS operational transconductance amplifier (OTA) using a fully differential single-stage core OTA as the input stage and a differential to single current converter as the output stage, each biased at a separate current level, is presented.
Rijns, J.J.F., Wallinga, H.
core +1 more source
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
Versatile Active Biquad Based on Dual-Output Second-Generation Current Conveyors
A universal active biquad based on the dual-output second-generation current-conveyor (CCII±) is presented. The circuit uses only six CCII± and can, simultaneously, support three mixed-mode transfer functions and five current-mode transfer functions ...
M. T. Abuelma'atti, H. A. Alzaher
doaj +1 more source
ECCCII-Based Current-Mode Universal Filter with Orthogonal Control of w_o and Q [PDF]
This paper presents a new current-mode current-controlled four-input five-output universal filter employing one current-controlled current conveyor (CCCII), one electronically tunable CCCII and two grounded capacitors. The proposed configuration provides
Junnapiya, S. +4 more
core +1 more source
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Next‐generation proteomics improves lung cancer risk prediction
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source

