Results 101 to 110 of about 676,492 (269)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

CPES : Center Program Snapshot (April 2009)

open access: yes, 2009
With the widespread use of power electronics technology, the United States would be able to cut electrical energy consumption by 33 percent. The energy savings, by today’s measure, is equivalent to the total output of 840 fossil fuel-based generating ...
Center for Power Electronics Systems
core  

Modeling and Transmission Characteristics Study of a Resonant Underwater Wireless Electric Power Transmission System

open access: yesEnergies
Compared to the traditional wet-mate underwater power supply method, Magnetic Coupling Resonant Wireless Power Transfer (MCR-WPT) technology boasts advantages such as excellent insulation, high safety, and convenient operation, showing promising ...
Qiong Hu   +5 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Nonlinear Output Feedback Droop Control for Parallel Inverters in Standalone Microgrids

open access: yes, 2019
This paper proposes a nonlinear control scheme for power-sharing between parallel distributed generations in a standalone microgrids. Generally, a linear control-based droop method is applied to balance the power in between multigenerating units and ...
Md Alamgir Hossain   +5 more
core   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

SiC and Si transistors comparison in boost converter

open access: yes, 2012
Development of new wide band gap (WBG) power devices, and among them, of Silicon Carbide (SiC) power devices, has been an active field of research during the last years.
Apiñaniz, Susana   +16 more
core   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

open access: yesFEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo   +7 more
wiley   +1 more source

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