Results 91 to 100 of about 23,414 (261)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Verbal Output Profile in Children with Attention Deficit Hyperactivity Disorder

open access: yesJournal of Communication Disorders, Deaf Studies & Hearing Aids, 2017
Communicative differences are a feature of ADHD and measuring differences in verbal behavior can elucidate critical features of the disorder. This study focuses on quantity of verbal output through investigating the verbal productivity and length of turns in children with ADHD compared to age-matched typically developing (TD) children. The participants
Al-Dakroury, Wael, Gardner, H.
openaire   +2 more sources

Analysis Of Output Voltage Profile Of Raindrop Impact Using Piezeolectric-Bridge Structure For Energy Harvesting [PDF]

open access: yes, 2016
This research focuses on the output voltage profile generated from the piezoelectric-bridge structure for a single drop and continuous drop. In this study, a 5.6 mm of water droplet was used to impact the PVDF material (polyvinylidene fluoride) of 30 mm ...
Hassan, Azlina
core  

Power output (watts) profile.

open access: yes, 2019
Power output for each participant and condition during the 20’ self-paced exercise. Dashed line represents the overall mean.
Mikel Zabala (165218)   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Output formats for collection-level descriptions from the SCONE database: report for Work Package B of the JISC CC-interop project [PDF]

open access: yes, 2004
This report forms part of deliverable B7 of the COPAC/Clumps Continuing Technical Cooperation project (CC-interop). Deliverable B7 consists of automated routines to allow the collection-level description (CLD) database of the Scottish Collections ...
Dunsire, Gordon
core  

Investigation of spatiotemporal output beam profile instabilities from differentially pumped capillaries

open access: yes, 2021
Differentially pumped capillaries, i.e., capillaries operated in a pressure gradient environment, are widely used for nonlinear pulse compression. In this work, we show that strong pressure gradients and high gas throughputs can cause spatiotemporal ...
Emmanuel B. Amuah (14384103)   +6 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

基于Romax与Kisssoft软件的齿形优化设计与分析

open access: yesJixie chuandong, 2011
By tooth profile optimization,tooth strength and the meshing quality can be improved.However,tooth profile optimization process is complex,and it needs a experienced designer to carry out a lot calculation.Now with variety of gear design software,a new ...
唐进元, 刘继凯, 雷敦财
doaj  

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