Results 121 to 130 of about 3,122,133 (254)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Modelling, evaluation and demonstration of novel active voltage control schemes to accomodate distributed generation in distribution networks [PDF]

open access: yes, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Voltage control in distribution networks is becoming more challenging due to the growing amount of distributed generation that is being connected to the ...
Fila, Maciej
core   +2 more sources

High-Efficiency, Low-Power, Fully Integrated Neural Electrical Stimulation Circuit

open access: yesApplied Sciences
This paper presents a highly efficient, low-power, fully integrated neural stimulation circuit implemented using solely low-voltage devices. The circuit primarily consists of a high-voltage-generation circuit, an output driver circuit, and a constant ...
Yujiao Wang, Jiahao Cheong, Cheng Liu
doaj   +1 more source

A 30% Efficient High-Output Voltage Fully Integrated Self-Biased Gate RF Rectifier Topology for Neural Implants. [PDF]

open access: yesIEEE J Solid-State Circuits, 2022
Xu Z   +8 more
europepmc   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

High Piezoelectric Output Voltage from Blue Fluorescent N,N-Dimethyl-4-nitroaniline Nano Crystals in Poly-L-Lactic Acid Electrospun Fibers. [PDF]

open access: yesMaterials (Basel), 2022
Baptista RMF   +11 more
europepmc   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Modeling and Control of DC to High-Frequency AC Voltage Conversion for Photovoltaic Systems Under Variable Irradiation, Temperature and Load Conditions

open access: yesElectrica
: This study introduces a model that adjusts the DC voltage output from PV panels through a Cuk Converter while a Class-E inverter produces a high-frequency AC voltage.
Fatih Issi, Mustafa Karhan
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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