Results 141 to 150 of about 1,988,507 (267)

How radiological findings and neurological disorders are related in congenital zika syndrome: A cohort study

International Journal of Infectious Diseases, 2020
N.N. Mendes Neto, J. Maia, M. Zacarkim, A.D. Labeaud, D. Aronoff   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Detection of zoonotic pathogens in invasive black rats (<i>Rattus rattus</i>) inside and outside a coastal protected area in southern Peru. [PDF]

Front Vet Sci
Calvo-Mac C, Silva-Caso W, Del Valle-Mendoza J, Tarazona-Castro Y, Condori J, Malaga-Machaca ES, Calderón M, Martínez-Ventura A, Tsukayama P, Cárdenas-Alayza S.   +9 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Factors associated with patient use of primary care outside of their capitated primary care enrolment group: Multilevel analysis. [PDF]

Can Fam Physician
Sibley LM, Shaikh S, Weir S, Alam N, Mathew S, Kantarevic J.   +5 more
europepmc   +1 more source

Outsider/Insider [PDF]

The American Journal of Bioethics, 2018
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Not Just a Matter of Space: Integrating Ecological Niche Modeling With Genotype-Environment Associations Suggests High Maladaptation Risks Under Climate Change for a Microendemic Malagasy Frog. [PDF]

Ecol Evol
Belluardo F, Di Febbraro M, Lobón-Rovira J, Oliveira Alves I, Rasoazanany M, Andreone F, Rosa GM, Giovacchini S, Mirone E, Singh Jamwal P, Afonso S, Innangi M, Sferra G, Trucchi E, Mondanaro A, Carotenuto F, Loy A, Crottini A.   +17 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source