Results 211 to 220 of about 385,031 (304)

Immune Checkpoint Inhibitors and Immunomodulators for Cancer Immunotherapy: Insights Into Resistance and Therapeutic Strategies

Advanced Science, Volume 13, Issue 25, 4 May 2026.
The schematic diagram illustrates the roles of novel immune checkpoints, immunomodulatory factors, cell death and multimodal technologies in cancer immunotherapy. Abstract Cancer immunotherapy has redefined cancer treatment. However, the molecular and cellular basis of immune evasion and therapeutic resistance remains incompletely understood.
Fangquan Chen, Yang Yu, Xiutao Cai, Junhao Lin, Ruirui Liang, Rui Kang, Daolin Tang, Jiao Liu   +7 more
wiley   +1 more source

Antigen-Containing Silk Nanoparticles: A New Potential as Oral Vaccine Carriers. [PDF]

Int J Nanomedicine
Sato M, Sakuma C, Sezutsu H, Kojima K.
europepmc   +1 more source

Rachipagus Parasitic Twin With Epithelialized Myelomeningocele in a Rural Ethiopian Neonate: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Rachipagus parasitic twinning is an exceptionally rare clinical entity resulting from an asymmetric monozygotic twinning process, characterized by a dorsally co‐joined partially formed twin. Co‐ existence of this condition with neural tube defect is uncommon, yet clinically significant.
Biruk Lealem, Elleni Tadesse, Bethelehem Engidawork   +2 more
wiley   +1 more source

XCR1+ and CD11b+ migratory dendritic cells cooperate for the cross-priming of intratumoral CD8+ T cells with a tissue-resident memory phenotype.

Guermonprez P, Vaudiau N, Bourdely P, Ok A, Semitekolou M, Gorline L, Savoldelli R, Gerber-Ferder Y, Carmo FD, Sémervil A, Vetillard M, Rood A, Bouallègue S, Pamboukas K, Bornères J, Darrasse-Jeze G, Gautier E, Dalod M, TARTOUR E, Bergsbaken T, Gisbergen Kv, Hodivala-Dilke K, Saveanu L, Helft J, Benvenuti F, Coulibaly A, Rastello M, Guillin M, Weber J, Abbas A, Garcia Z, Ginhoux F, Bleriot C, Bousso P, Kumamoto Y, Mazzone M.   +35 more
europepmc   +1 more source

Acepromazine Reduces Airway Contraction in a Murine Model of Asthma. [PDF]

Clin Exp Pharmacol Physiol
Lino-Alvarado A, de Oliveira MA, Serra CSM, Melhado IVS, Campos R, Riffo-Vasquez Y, Moriya HT.   +6 more
europepmc   +1 more source

Pulmonary Aspergillosis Treated With Oral Amphotericin B (MAT2203) in a Patient With HIV‐Related Cryptococcal Meningitis

Clinical Case Reports, Volume 14, Issue 5, May 2026.
Graphical abstract for a case of a 26‐year‐old female with advanced HIV disease, cryptococcal meningitis, and co‐infection with pulmonary aspergillosis. Both co‐infections were successfully treated with the novel oral lipid nanocrystal formulation of amphotericin B (MAT2203).
Enock Kagimu, Elizabeth Senkoro, Jane Gakuru, Morris K. Rutakingirwa, David R. Boulware, David B. Meya, Richard Kwizera   +6 more
wiley   +1 more source

Single-cell transcriptome sequencing reveals immunological mechanisms by which recombinant Echinococcus granulosus P29 protein alleviates airway inflammation in mice with allergic asthma. [PDF]

Parasit Vectors
Zhou Z, Wu J, Fu L, Wen R, Zhang X, Dang Z, Wu J, Bao S, Li W, Yin M, Gao X, Zhao J.   +11 more
europepmc   +1 more source

Dual‐Function Lipid‐Based Nanovector Strategy for Glioblastoma Immunotherapy: STING Activation and M1 Microglia Polarization

Drug Development Research, Volume 87, Issue 3, May 2026.
ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain malignancies because of its highly immunosuppressive tumor microenvironment and the limited penetration of therapeutics across the blood‐brain barrier (BBB). Although recent studies have separately explored STING agonism, microglial reprogramming, and nanocarrier‐based drug delivery, an ...
Mohamed S. Nafie, Mohamed Khaled Diab, Sherif Ashraf Fahmy   +2 more
wiley   +1 more source

Mechanistic insight into the anti-inflammatory and lung-protective effects of <i>Agrimonia pilosa</i> extract via NF-κB/MAPK inhibition in ovalbumin- and lipopolysaccharide-induced respiratory inflammation models. [PDF]

Pharm Biol
Lee YG, Kwon JE, Park DW, Lee HR, Lee J, Choi YM, Cho EJ, Kang SC.   +7 more
europepmc   +1 more source

Unveiling CLC as a Central Regulator of Allergic Rhinitis via the CLC‐CCL26/POSTN Axis: An Integrated Bioinformatics and Experimental Study

Flavour and Fragrance Journal, Volume 41, Issue 3, Page 696-710, May 2026.
We unveil that CLC orchestrates the dual role of eosinophil recruitment via CCL26 and tissue remodelling via POSTN in allergic rhinitis, identifying it as a potential therapeutic target. ABSTRACT Allergic rhinitis (AR) is a chronic airway inflammation driven by a type 2 immune response, yet the molecular mechanisms underlying its persistence and tissue
Fanyu Yuan, Yuhan Dong, Zishuo Guo, Xiaodong Zhao, Jian Liu, Fangyuan Zhu, Shengjie Ge, Chengcheng Liu, Shuai Xu, Ming Xia   +9 more
wiley   +1 more source