Results 151 to 160 of about 769,731 (345)

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

High incidence of silent venous thromboembolism before treatment in ovarian cancer [PDF]

, 2007
Toyomi Satoh, Akinori Oki, K. Uno, M Sakurai, Hiroyuki Ochi, Satoshi Okada, Rie Minami, Koji Matsumoto, Yumiko Tanaka, Hajime Tsunoda, Sachiko Homma, Hiroyuki Yoshikawa   +11 more
openalex   +1 more source

#931 Clinical implications of spatial intra-tumoural heterogeneity on homologous recombination deficiency scores in high grade serous ovarian cancer [PDF]

, 2023
Christina Fotopoulou, Elizabeth L. Christie, Marc Lorentzen, Maiqi Liu, Edward Curry, Chun Hei Kwok, Ahwan Pandey, Katherine Nixon, Jennifer Ploski, James Clark, Iain A. McNeish, Jonathan Krell   +11 more
openalex   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

A Case of pseudo-Meigs' Syndrome Due to Ovarian Metastasis of Sigmoid Colon Cancer

, 2007
Gakuji Osawa, K. Yoshimatsu, Hajime Yokomizo, Takahiro Fujimoto, Akiyo Matsumoto, T Otani, Arihiro Umehara, Katsuhiro Ogawa   +7 more
openalex   +2 more sources

Multifunctional Polymeric Micelles Co-loaded with Anti–Survivin siRNA and Paclitaxel Overcome Drug Resistance in an Animal Model of Ovarian Cancer [PDF]

, 2015
Giuseppina Salzano, Gemma Navarro, Malav Trivedi, Giuseppe De Rosa, Vladimir P. Torchilin   +4 more
openalex   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

High‐Throughput 3D Matrigel‐based Droplet Microfluidics for Single‐Cell Function‐to‐Omics Analysis of Cytotoxic Immune Cells in Solid Tumor Interactions

Advanced Materials Technologies, EarlyView.
A 3D Matrigel‐based droplet microfluidics platform that allows physiologically relevant analysis of single immune‐tumor interactions in solid tumors. By integrating real‐time functional imaging with fluorescence‐activated droplet sorting and RNA sequencing, the system links immune cytotoxic behavior to transcriptomic profiles, providing a scalable ...
Christina Sharkey, Harry Akligoh, Michael Finocchiaro, Abhishek Srihari Rampelli, Zongwei Wang, Aria F. Olumi, Tania Konry   +6 more
wiley   +1 more source

Wilms’ tumor 1 (WT1) promotes ovarian cancer progression by regulating E-cadherin and ERK1/2 signaling

, 2020
Yun Han, Chao Song, Tingting Zhang, Qianqian Zhou, Xiaoqian Zhang, Jing Wang, Boqun Xu, Xuesen Zhang, Xiaoqiu Liu, Xiaoyan Ying   +9 more
openalex   +1 more source

Network-based survival-associated module biomarker and its crosstalk with cell death genes in ovarian cancer [PDF]

, 2015
Nana Jin, Hao Wu, Zhengqiang Miao, Yan Huang, Yongfei Hu, Xiaoman Bi, Deng Wu, Kun Qian, Liqiang Wang, Changliang Wang, Hongwei Wang, Kongning Li, Xia Li, Dong Wang   +13 more
openalex   +1 more source