Results 191 to 200 of about 769,731 (345)

BRCA2 Status Alters the Effect of the P53 Reactivator HO-3867 in Ovarian Cancer Cells

, 2023
Eric J. Devor, Ariane E Thomas, Brandon Schickling   +2 more
openalex   +1 more source

De Novo Design and Directed Evolution Refinement of Mirror‐Image Protein Binders Targeting Interleukin‐4

Advanced Science, EarlyView.
This study presents the de novo design and directed evolution of a mirror‐image D‐protein inhibitor targeting human interleukin‐4 (IL‐4). The engineered molecule exhibits nanomolar binding affinity for IL‐4 and effectively inhibits IL‐4–mediated signaling.
Liqing Xu, Yuxiang Ren, Tongyue Wang, Hongyong Li, Yue Yao, Lei Liu, Ke Sun, Peilong Lu   +7 more
wiley   +1 more source

Correction: Wip1 suppresses angiogenesis through the STAT3-VEGF signalling pathway in serous ovarian cancer

Journal of Ovarian Research, 2022
Sheng Yin, Lina Yang, Yiyan Zheng, Rongyu Zang   +3 more
doaj   +1 more source

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

Hereditary ovarian cancer. [PDF]

Discov Oncol
Jurgiel WA, Panasiuk B, Posmyk R.
europepmc   +1 more source

39 Interim analysis of ovarian cancer by the us national cancer moonshot’s tri-federal (DOD/NCI/VA) applied proteogenomic organizational learning and outcomes (APOLLO) research network [PDF]

, 2019
GL Maxwell, NW Bateman, A. R. Soltis, G Wang, CL Dalgard, EF Petricoin, CM Tarney, C. Rojas, Laura J. Havrilesky, D. E. Cohn, JM Wells, Hai Hu, CA Hamilton, CD Shriver, Matthew D. Wilkerson, Yovanni Casablanca, Kathleen M. Darcy, T P Conrads   +17 more
openalex   +1 more source

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

Advanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He, Anqi Zhang, Zhanchen Guo, Qi Li, Song Gao, Wenyan Guan, Ying Li, Jingran Chen, Sijia Sun, Jian He, Zhen Liu   +10 more
wiley   +1 more source

The influence of aspects of the biophysical environment on ovarian cancer cell behaviour

, 2020
Mian Makhdoom Sarwar
openalex   +1 more source

A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes

Advanced Science, EarlyView.
We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen, Zixing Xu, Zerun Hao, Yanming Chen, Kai Xie, Haofan Yin, Xueying Wang, Jie Min, Sihan Sun, Baiding Chen, Chengxiu Ling, Mingming Xu, Yizhao Chen, Gang Ruan   +13 more
wiley   +1 more source

Longer-term aspirin use and subsequent ovarian cancer risk in the Ovarian Cancer Cohort Consortium. [PDF]

Int J Epidemiol
Hurwitz LM, O'Brien KM, Townsend MK, Reid BM, Fridley BL, Fan W, Schabath MB, Bodelon C, Chan AT, Fortner RT, Håkansson N, Harris HR, Lacey JV, Liao LM, Merritt MA, Patel AV, Poynter JN, Robien K, Sandler DP, Wentzensen N, Wolk A, Zheng W, Tworoger SS, Trabert B.   +23 more
europepmc   +1 more source