Results 241 to 250 of about 769,731 (345)

Diagnostic Timing and Ovarian Cancer Survival.

JAMA Netw Open
Soppe SE, Kuo TM, Bae-Jump VL, Albright BB, Lyratzopoulos G, Baggett CD, Thompson CA.   +6 more
europepmc   +1 more source

Inhibition of CDK9 sensitizes multidrug resistant ovarian cancer cells to paclitaxel. [PDF]

Sci Rep
Wang J, Hornicek FJ, Shi H, Feng W, Duan Z.   +4 more
europepmc   +1 more source

Selective Targeting of Immune Checkpoints HLA‐G and CD47 Using Novel Dual Signaling Protein DSP216 Promotes Innate Anticancer Immunity

Advanced Science, EarlyView.
The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob, Liat Tamir, Mufeed Abdeen, Ami Tamir, Alexandra Aronin, Itai Bloch, Roy Kahn, Iris Pecker, Mark Tykocinski, Gerwin Huls, Yaron Pereg, Ayelet Chajut, Edwin Bremer   +12 more
wiley   +1 more source

Identifying the best diagnostic test for ovarian cancer - synopsis of Refining Ovarian Cancer Test accuracy Scores (ROCkeTS) research.

Health Technol Assess
Sundar S, Agarwal R, Scandrett K, Davenport C, Sturdy L, Ottridge R, Deeks J, ROCkeTS collaborators.   +7 more
europepmc   +1 more source

Integrative Oncology for Biochemical Recurrence of Epithelial Ovarian Cancer. [PDF]

Curr Oncol Rep
Berman T, Matanes E, David CB, Frenkel M.   +3 more
europepmc   +1 more source

Dose‐Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload

Advanced Science, EarlyView.
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li, Yaoqiu Wu, Guangyu Yang, Jingyi Lai, Xiaoyue Sun, Liyan Wang, Xiaoli Li, Jing Zhang, Qingxue Zhang, Hui Chen, Haiyan Lin, Bingxiang Xu, Junfeng Zhang, Hailong Wang, Anming Meng, Chunwei Cao   +15 more
wiley   +1 more source

Early Detection and Prevention of Ovarian Cancer. [PDF]

Cancers (Basel)
Montemorano L, Huffman L, Barroilhet L.
europepmc   +1 more source

EIF5A1 promotes epithelial ovarian cancer proliferation and progression

, 2018
Jing Zhang, Xiao Li, Xiaorui Liu, Fu‐Ju Tian, Weihong Zeng, Xiaowei Xi, Yi Lin   +6 more
openalex   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Mitochondrial apoptosis gene-based pathomics for ovarian cancer prognosis. [PDF]

Sci Rep
Qin LH, Huang X, Yang C, Song R, Chen PY, Jiang Z, Xu W, Zeng G, Chen H, Long L.   +9 more
europepmc   +1 more source