Results 271 to 280 of about 5,260,709 (398)

STING Agonists and How to Reach Their Full Potential in Cancer Immunotherapy

Advanced Science, Volume 12, Issue 17, May 8, 2025.
STING agonists show promise in preclinical studies in boosting an anti‐tumor response using the immune system. However, different limitations remain, and future research is needed to better understand how STING activation impacts the tumor microenvironment, identify effective combination strategies, and determine the best tumor types for STING agonist ...
Laura Gehrcken, Christophe Deben, Evelien Smits, Jonas R.M. Van Audenaerde   +3 more
wiley   +1 more source

Characterizing somatic mutations in ovarian cancer germline risk regions. [PDF]

Commun Biol
Lai PH, Tyrer JP, Pharoah P, Gayther SA, Jones MR, Peng PC.   +5 more
europepmc   +1 more source

“Second-look” procedures in the management of ovarian cancer

, 1983
Carlo La Vecchia, Silvia Franceschi, Alessandro Liberati   +2 more
openalex   +1 more source

scCompass: An Integrated Multi‐Species scRNA‐seq Database for AI‐Ready

Advanced Science, EarlyView.
scCompass integrates and standardizes transcriptomic data from ≈105 million single cells across 13 species, enabling the identification of stable expression genes and organ‐specific expression genes in humans and mice. It provides scalable datasets for AI model training, pretrained model checkpoints, and user‐friendly platforms for data sharing ...
Pengfei Wang, Wenhao Liu, Jiajia Wang, Yana Liu, Pengjiang Li, Ping Xu, Wentao Cui, Ran Zhang, Qingqing Long, Zhilong Hu, Chen Fang, Jingxi Dong, Chunyang Zhang, Yan Chen, Chengrui Wang, Guole Liu, Hanyu Xie, Yiyang Zhang, Meng Xiao, Shubai Chen, Haiping Jiang, The X‐Compass Consortium, Yiqiang Chen, Ge Yang, Shihua Zhang, Zhen Meng, Xuezhi Wang, Guihai Feng, Xin Li, Yuanchun Zhou   +29 more
wiley   +1 more source

The impact of preoperative immunonutritional status on postoperative complications in ovarian cancer. [PDF]

J Ovarian Res
Liu X, Li M, Zhao Y, Jiao X, Yu Y, Li R, Zeng S, Chi J, Ma G, Huo Y, Peng Z, Liu J, Zhou Q, Zou D, Wang L, Li Q, Wang J, Yao S, Chen Y, Ma D, Hu T, Gao Q.   +21 more
europepmc   +1 more source

Histochemical distribution of CA-125 as a prognostic indicator in patients with serous ovarian cancer [PDF]

, 1991
P. Bichel, Anders Jakobsen, Torben F. Ørntoft   +2 more
openalex   +1 more source

The INAVA mRNA in Extracellular Vesicles Activates Normal Ovarian Fibroblasts by Phosphorylation–Ubiquitylation Crosstalk of HMGA2

Advanced Science, EarlyView.
Ovarian cancer‐derived extracellular vesicles (EVs) transfer INAVA mRNA to normal ovarian fibroblasts (NOFs). Translated INAVA protein inhibits HMGA2 phosphorylation‐dependent ubiquitylation and proteasomal degradation, promoting NOF activation.
Lingkai Gu, Zhangjin Shen, Shizhen Shen, Conghui Wang, Yuwan Liu, Xinyi Wei, Mengxia Zheng, Jiaxin Gu, Xiaojing Chen, Yi Sun, Junfen Xu, Yan Lu, Weiguo Lu   +12 more
wiley   +1 more source

Identification of a cuproptosis‑related prognostic biomarker and therapeutic target in ovarian cancer. [PDF]

Oncol Lett
Chen B, Yuan S, Wang H.
europepmc   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

The Role of CA-125 in the Management of Ovarian Cancer: A Systematic Review. [PDF]

Cancer Rep (Hoboken)
Momenimovahed Z, Mazidimoradi A, Allahqoli L, Salehiniya H.   +3 more
europepmc   +1 more source