Results 291 to 300 of about 5,108,464 (344)

Recent Advancements in Topic Modeling Techniques for Healthcare, Bioinformatics, and Other Potential Applications

open access: yesAdvanced Intelligent Systems, EarlyView.
This article offers a comprehensive review of topic modeling techniques, tracing their evolution from inception to recent developments. It explores methods such as latent Dirichlet allocation, latent semantic analysis, non‐negative matrix factorization, probabilistic latent semantic analysis, Top2Vec, and BERTopic, highlighting their strengths ...
Pratima Kumari   +6 more
wiley   +1 more source

Clinlabomics‐Enabled Blending Ensemble Learning for Low‐Cost Pan‐Cancer Detection and Classification Using Routine Clinical Laboratory Data

open access: yesAdvanced Intelligent Systems, EarlyView.
Researchers develop clinlabomics assisted for cancer identification, an artificial intelligence‐powered system using routine clinical lab data to detect and identify 10 cancer types. Tested on 19 199 individuals, it achieves 90.39% sensitivity and 82.41% specificity in cancer detection, with 72.57% accuracy in identifying specific cancer types ...
Bowen Zhang   +9 more
wiley   +1 more source

Facts and Misfacts on D‐Dimer Testing. Consensus Guidance From the Italian Society on Thrombosis and Hemostasis (SISET)

open access: yesAmerican Journal of Hematology, EarlyView.
ABSTRACT D‐dimer defines degradation products derived from the proteolysis mediated by plasmin on cross‐linked fibrin. The evidence‐based use of D‐dimer in some conditions has been consolidated. Currently, however, there is an entrenched prescription of D‐dimer testing to screen otherwise healthy subjects that may induce prescribing physicians to start
Armando Tripodi   +11 more
wiley   +1 more source

Outcomes from a Novel Approach to Studying Consumer Genetic Testing for Germline Cancer and Cardiovascular Risk

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Despite the growing availability of consumer genetic testing for serious disease risks, outcomes data remain limited for individuals undergoing testing for high‐ and moderate‐penetrance genes. To address this gap, we evaluated the feasibility of the Consumer Genetic Testing Outcomes Evaluation Paradigm (CGT‐OEP), a novel approach for studying ...
Madison K. Kilbride   +6 more
wiley   +1 more source

The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The flow diagram outlines the chemical induction of breast tumors through a single intraperitoneal dose of MNU. Tumor development was assessed using ultrasound and clinical examination. After 14 weeks, mammary tissue was collected and histologically analyzed to evaluate structural similarities between sows and humans, the carcinogenic potential of MNU,
Claudia Elizabeth Vera‐Tizatl   +6 more
wiley   +1 more source

Vitamin D‐induced mechanisms in cancer prevention and therapy: Recent advances and future opportunities

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Vitamin D, traditionally known to promote calcium and bone health, is being explored for its role in cancer prevention and treatment through its influence on cell proliferation, differentiation, apoptosis, and immune response. The vitamin D receptor (VDR) regulates gene expression and interacts with key signaling pathways such as Wnt/β‐catenin, MAPK ...
D. Prasanth   +10 more
wiley   +1 more source

Emerging Strategies for Platelet‐Modified Nanoparticles in Targeted Tumor Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights innovative strategies using platelet‐modified nanoparticles to target tumors more precisely. By mimicking platelet functions, these biomimetic carriers improve tumor homing, enhance drug delivery, and reduce immune clearance.
Chunyu Bai   +5 more
wiley   +1 more source
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Ovarian cancer today and tomorrow: A global assessment by world region and Human Development Index using GLOBOCAN 2020

International Journal of Cancer, 2022
Ovarian cancer remains to have relatively poor prognosis particularly in low‐resourced settings. It is therefore important to continually examine the burden of ovarian cancer to identify areas of disparities.
C. Cabasag   +8 more
semanticscholar   +1 more source

Ovarian Cancer

Critical Reviews in Oncology/Hematology, 2006
Ovarian cancer accounts for 4% of all cancers in women and is the leading cause of death from gynaecologic malignancies. Because early-stage ovarian cancer is generally asymptomatic, approximately 75% of women present with advanced disease at diagnosis. Survival is highly dependent on stage of disease: 5-year survival in patients with early-stage is 80-
Pat J. Morin, Ellen S. Pizer
openaire   +3 more sources

Ovarian Cancer

Surgical Oncology Clinics of North America, 1998
Ovarian cancer is the leading cause of death in women with pelvic malignancies. Because of the multiple histologic types of malignancy that can arise within the ovary, accurate diagnosis and staging is critical for optimal patient care. The current standard of proper surgical management followed by combination chemotherapy is outlined.
W, Gajewski, R D, Legare
openaire   +2 more sources

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