Results 331 to 340 of about 5,337,944 (374)

The Role of CAF‐derived Vitronectin in Promoting Colorectal Cancer Progression and Immunosuppression

Advanced Science, EarlyView.
Cancer‐associated fibroblast (CAF)‐derived VTN upregulates SLC6A8 expression in colorectal cancer (CRC) cells and macrophages through enhanced FAK phosphorylation. This modulation significantly increases the cellular uptake of creatine and ATP, promoting cancer progression and macrophage polarization.
Jiahua Yu, Mengxi Xiu, Shijun Yu, Zhiqin Chen, Yandong Li, Yong Gao   +5 more
wiley   +1 more source

Immunotherapy in Recurrent Ovarian Cancer. [PDF]

Biomedicines
Chen K, Wang J, Yang M, Deng S, Sun L.
europepmc   +1 more source

Tumor Small Extracellular Vesicle‐Transmitted LncRNA CATED Promotes Platinum‐Resistance in High‐Grade Serous Ovarian Cancer

Advanced Science, EarlyView.
Overcoming platinum resistance in high‐grade serous ovarian cancer (HGSOC) is critical for improving outcomes. This study identifies lncRNA CATED, elevated in platinum‐resistant small extracellular vesicles (sEVs) and tumors, which drives cisplatin resistance by enhancing DHX36 SUMOylation, boosting RAP1A translation, and activating MAPK signaling ...
Yi Liu, Hanyuan Liu, Chenchen Zhu, Yan Yang, Zhen Shen, Ge Shan, Liang Chen, Ying Zhou   +7 more
wiley   +1 more source

Diet and survival after a diagnosis of ovarian cancer: a pooled analysis from the Ovarian Cancer Association Consortium. [PDF]

Am J Clin Nutr
Nagle CM, Ibiebele TI, Na R, Bandera EV, Cramer D, Doherty JA, Giles GG, Goodman MT, Hanley GE, Harris HR, Jensen A, Kjaer SK, Lee A, McGuire V, Milne RL, Qin B, Richardson J, Sasamoto N, Schildkraut JM, Sieh W, Terry KL, Titus L, Trabert B, Wentzensen N, Wu AH, Berchuck A, Pike MC, Pearce CL, Webb PM, Multidisciplinary Ovarian Cancer Outcomes Group and Ovarian Cancer Association Consortium.   +29 more
europepmc   +1 more source

Microfluidic Biochip‐Based Multiplexed Profiling of Small Extracellular Vesicles Proteins Integrated with Machine Learning for Early Disease Diagnosis

Advanced Science, EarlyView.
This study develops a diagnostic platform for early detection of esophageal squamous cell carcinoma (ESCC) by integrating a barcode immunoassay biochip with machine learning. The biochip captures and analyzes small extracellular vesicle proteins from serum samples, identifying nine biomarkers linked to ESCC.
Xue Zhang, Yibin Jia, Zhikai Li, Yunhong Zhang, Chao Wang, Yanbo Liang, Jiaoyan Qiu, Mingyuan Sun, Xiaoshuang Chen, Miao Huang, Yu Zhang, Jianbo Wang, Hong Liu, Chuanbin Mao, Lin Han   +14 more
wiley   +1 more source

Influence of Age on Treatment and Prognosis in Ovarian Cancer Patients. [PDF]

Cancers (Basel)
Mancebo G, Sole-Sedeno JM, Fabregó B, Pinto G, Vizoso A, Alvarez M, Sabaté-Garcia RA, Miralpeix E.   +7 more
europepmc   +1 more source

Circulating Tumor Cells Shed Shearosome Extracellular Vesicles in Capillary Bifurcations That Activate Endothelial and Immune Cells

Advanced Science, EarlyView.
Using microfluidic models of capillary networks, this study discovered that fluid shear stresses on circulating tumor cells transiting through capillary‐sized bifurcations shed a novel class of shear‐dependent large extracellular vesicle, “shearosomes”, whose proteome comprises of over 3000 distinct proteins.
Angelos Vrynas, Salime Bazban‐Shotorbani, Sara Arfan, Karishma Satia, Brian Cunningham, Gauhar Sagindykova, Mymuna Ashna, Aoyu Zhang, Diana Visan, Aisher Chen, Teige Matthews‐Palmer, Mathew Carter, Fiona Blackhall, Kathryn L. Simpson, Caroline Dive, Paul Huang, Sam H. Au   +16 more
wiley   +1 more source

Ovarian Cancer-Epidemiology, Classification, Pathogenesis, Treatment, and Estrogen Receptors' Molecular Backgrounds. [PDF]

Int J Mol Sci
Smolarz B, Biernacka K, Łukasiewicz H, Samulak D, Piekarska E, Romanowicz H, Makowska M.   +6 more
europepmc   +1 more source

GANT61 Modulates Autophagy and Lipid Metabolism in Ovarian Cancer. [PDF]

Cell Prolif
Pan Y, Chen L, Shen J, Hong S, Guan X, Ma X, Tang R, Lu M, Sun F, Shang S, Dai Y, Zhou Z, Zhang S, Yang J.   +13 more
europepmc   +1 more source