Results 361 to 370 of about 5,260,709 (398)

Unnatural Triggers Converted From Tetrazine‐Attached Sialic Acid for Activation of Optoacoustic Imaging‐Guided Cancer Theranostics

Angewandte Chemie, EarlyView.
Tetrazine precursors (SiaTz) based on a nonO‐acetylated sialic acid scaffold are rationally designed and synthesized, which can be efficiently converted into unnatural tetrazine (Tz) triggers on cancer cell surfaces via metabolic glycoengineering. These Tz triggers activate theranostic agents for multispectral optoacoustic tomographic (MSOT) imaging ...
Yinglong Wu, Lihe Sun, Xiaodong Zhang, Wenbin Zhong, Xiaokai Chen, Shihuai Wang, Yun Chen, Dongdong Wang, Ting He, Hongzhong Chen, Jingjing Guo, Fang Zeng, Menghuan Li, Zhong Luo, Shuizhu Wu, Yanli Zhao   +15 more
wiley   +1 more source

Modern Emerging Biosensing Methodologies for the Early Diagnosis and Screening of Ovarian Cancer. [PDF]

Biosensors (Basel)
Abul Rub F, Moursy N, Alhedeithy N, Mohamed J, Ifthikar Z, Elahi MA, Mir TA, Rehman MU, Tariq S, Alabudahash M, Chinnappan R, Yaqinuddin A.   +11 more
europepmc   +1 more source

The ATM Kinase Inhibitor AZD0156 is a Potent Inhibitor of Plasmodium Phosphatidylinositol 4‐Kinase (PI4Kβ) and is an Attractive Candidate for Medicinal Chemistry Optimisation Ag…

Angewandte Chemie International Edition, Accepted Article.
New compounds targeting human malaria parasites are critical for effective malaria control and elimination. Here, we pursued the imidazoquinolinone AZD0156 (MMV1580483), a human ataxia‐telangiectasia mutated (ATM) kinase inhibitor that completed Phase I clinical trials as an anticancer agent.
John G. Woodland, Dina Coertzen, Kathryn J. Wicht, Virginia Franco Hidalgo, Charisse Flerida A. Pasaje, Luiz C. Godoy, Tarrick Qahash, Mmakwena M. Mmonwa, Godwin A. Dziwornu, Lynn Wambua, Sarah Harries, Constance M. Korkor, Mathew Njoroge, Liezl Gibhard, Dale Taylor, Meta Leshabane, Henrico Langeveld, Tayla Rabie, Janette Reader, Mariëtte van der Watt, Nelius Venter, Erica Erlank, Ayesha S. Aswat, Lizette L. Koekemoer, Tomas Yeo, Jin H. Jeon, David A. Fidock, Francisco Javier Gamo, Sergio Wittlin, Jacquin C. Niles, Manuel Llinas, Lauren B. Coulson, Lyn-Marié Birkholtz, Kelly Chibale   +33 more
wiley   +1 more source

Identification of FLYWCH1 as a regulator of platinum-resistance in epithelial ovarian cancer. [PDF]

NAR Cancer
Fullstone TL, Rohm H, Kaltofen T, Hierlmayer S, Reichenbach J, Schweikert S, Knodel F, Loeffler AK, Mayr D, Jeschke U, Mahner S, Kessler M, Trillsch F, Rathert P.   +13 more
europepmc   +1 more source

Alternative splicing in ovarian cancer. [PDF]

Cell Commun Signal
Wei L, Li Y, Chen J, Wang Y, Wu J, Yang H, Zhang Y.   +6 more
europepmc   +1 more source

Role of KLF5 in enhancing ovarian cancer stemness and PARPi resistance: mechanisms and therapeutic targeting. [PDF]

J Transl Med
Xiao H, Cheng G, Zhang H, Liu Y, Chen Z, Gao Y, Gao F, Liu Y, Wang S, Kong B.   +9 more
europepmc   +1 more source

Characterization of lncRNAs contributing to drug resistance in epithelial ovarian cancer. [PDF]

Med Oncol
Siahestalkhi EK, Demiray A, Yaren A, Demiray AG, Tan S, Akça H.   +5 more
europepmc   +1 more source

RETRACTION: Enhancing Wound Healing and Overcoming Cisplatin Resistance in Ovarian Cancer. [PDF]

Int Wound J
europepmc   +1 more source

Molecular characteristics of early- and late-onset ovarian cancer: insights from multidimensional evidence. [PDF]

J Ovarian Res
Shen Y, Cheng J, Ding Q, Tao Z.
europepmc   +1 more source