Results 241 to 250 of about 42,242 (289)

Plasmonic Mesoporous Gold‐Based SERS Biosensor for Ovarian Cancer‐Derived Extracellular Vesicles

open access: yesSmall, EarlyView.
The nanoengineered mesoporous gold (mAu)‐based SERS platform enables rapid, sensitive detection of PLAP‐positive extracellular vesicles (EVs) in ovarian cancer (OC), with detection limits as low as 100 EVs mL−1. Achieving over 80% sensitivity and 98% specificity in clinical samples, this cost‐effective, non‐invasive tool shows promise for early cancer ...
Javeria Bashir   +16 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

The Ultrasonography Characteristics of Borderline Ovarian Tumor Subtypes

open access: yes
Journal of Ultrasound in Medicine, EarlyView.
Roni Yoeli‐Bik   +6 more
wiley   +1 more source

The Internal Nanostructure of Lipid Nanoparticles Influences Their Diverse Cellular Uptake Pathways

open access: yesSmall, EarlyView.
Lipid nanoparticles are vital for drug delivery, but their cellular interactions remain unclear. This study shows that non‐lamellar lyotropic liquid crystalline nanoparticles (LLCNPs) ‐ including cubosomes, hexosomes, and micellar cubosomes ‐ preferentially use passive pathways like membrane fusion, bypassing endocytic recycling faced by lamellar ...
Sue Lyn Yap   +7 more
wiley   +1 more source

Ultrasonic detection of bilateral ovarian cysts in the fetus

open access: bronze, 1982
Pentti Jouppila   +2 more
openalex   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

Understanding of endo/lysosomal escape of nanomaterials in biomedical application

open access: yesSmart Molecules, EarlyView.
This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang   +3 more
wiley   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

open access: yesSmall Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles(LNPs)and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu   +6 more
wiley   +1 more source

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