Results 241 to 250 of about 86,402 (307)
Small, EarlyView.This study uses advanced microscopy techniques, including transmission electron microscopy, scanning electron microscopy (SEM), cryogenic SEM, and live‐cell fluorescence imaging, to investigate lipid cubosome interactions with mammalian cells. It provides the first direct nanoscale evidence of cubosome membrane fusion with plasma and endosomal ...
Sue Lyn Yap +5 more
wiley +1 more source
Cellular Responses to Nanoscale Topography Mediated Through the RhoA/ROCK Pathway
Small, EarlyView.The most common ways that cells respond to nanoscale patterns include cytoskeletal reorganization, reduction in focal adhesion density, and increased endocytosis. Here RhoA is identified as a single biological pathway that can unify cellular responses to nanotopography.
Erik N. Schaumann +2 more
wiley +1 more source
Ultrasonic detection of bilateral ovarian cysts in the fetus
, 1982 Pentti Jouppila +2 more
openalex +1 more source
Small, EarlyView.A. Synthetic biology and biomaterials have emerged as tools to study and facilitate the treatment of solid tumors wi‐th chimeric antigen receptor‐CAR‐T cells. These strategies aim to resist the tumor microenvironment‐TME that presents cellular, biochemical, and mechanical immunosuppressive signals that hinder CAR‐T efficacy. B.
Grazia Marsico +2 more
wiley +1 more source
Understanding of endo/lysosomal escape of nanomaterials in biomedical application
Smart Molecules, EarlyView.This review summarized mainstream mechanisms of endo/lysosomal escape and design strategies of endo/lysosomal escapable nanoparticles in view of surface charge, polarity & hydrophobicity, particle morphology, and lysosomal escape agents. The utilization of endo/lysosomal escapable nanoparticles for vaccine delivery and genetic engineering are ...
Xin Wang +3 more
wiley +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, EarlyView.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
United European Gastroenterology Journal, EarlyView.ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n
Lichieh Julie Chu +6 more
wiley +1 more source