Results 261 to 270 of about 42,242 (289)

Cathepsin B Regulates Ovarian Reserve Quality and Quantity via Mitophagy by Modulating IGF1R Turnover

open access: yesAging Cell, EarlyView.
Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty   +8 more
wiley   +1 more source

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

open access: yesAging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar   +18 more
wiley   +1 more source

‘I Wish I Fought for Myself More Instead of Just Letting Doctors Dismiss Me’: A Combined Qualitative Analysis of Four Cohorts of Aotearoa New Zealand Endometriosis Patients

open access: yesAustralian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background Endometriosis is a chronic condition that affects around 10% of New Zealand women and people presumed female at birth, however, limitations in diagnosis and management mean patients wait a decade on average from symptom onset to diagnosis.
Katherine Ellis, Rachael Wood
wiley   +1 more source
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Management of ovarian cysts

Acta Obstetricia et Gynecologica Scandinavica, 2004
Background.  The treatment of an ovarian cyst relies on its nature, and accurate preoperative discrimination of benign and malignant cysts is therefore of crucial importance. This study was undertaken to review the literature concerning the preoperative diagnosis and treatment of ovarian cysts.Methods.
Knudsen, Ulla Breth   +7 more
openaire   +5 more sources

Ovarian Cysts and Ovarian Cancer

InnovAiT: Education and inspiration for general practice, 2009
Ovarian cysts and tumours are a relatively common finding among women of many ages, particularly with the wider use of regular physical examinations and ultrasound. Although the finding of an ovarian mass can be a source of considerable anxiety, most of those in younger women are not malignant and may be able to be managed entirely within primary care.
Shiner, Alice, Burbos, Nikolaos
openaire   +3 more sources

Ovarian cysts in newborns

Pediatric Surgery International, 2001
Before the introduction of ultrasonography (US), ovarian cysts in newborns were thought to be rare. With the extended use of real-time US, prenatal detection has increased. There is still considerable controversy regarding the best treatment of these neonatal findings.
A Piscopo, C Chiaramonte, F. Cataliotti
openaire   +3 more sources

Ovarian cysts

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1996
The Author intends to compare the data available in literature on the topic of 'laparoscopic surgery of ovarian cysts' to his case material. From 1985 to 1994, the author carried out 920 laparoscopic operations for the removal of ovarian cysts. Of these, 13 were converted to laparotomies, mostly because of peri-adnexal adhesions.
openaire   +2 more sources

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