Results 111 to 120 of about 561,797 (422)

A Case of Prader‐Willi Syndrome With a Deletion Including MAGEL2, NDN, and MKRN3, but Excluding SNRPN and SNORD116

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Prader‐Willi syndrome (PWS) is a neurodevelopmental disorder typically caused by large deletions or imprinting defects on chromosome 15q11.2, encompassing multiple genes. While the contribution of individual genes to the PWS phenotype remains unclear, previous studies suggested that isolated deletions of MAGEL2, NDN, and MKRN3, excluding the ...
Jannis Buecking, Yu An, Weimin Bi, Katrin Hinderhofer, Susanne Theiß, Anne Slavotinek, Christian P. Schaaf   +6 more
wiley   +1 more source

Is in utero exposure to maternal socioeconomic disadvantage related to offspring ovarian reserve in adulthood?

Women's Midlife Health, 2018
Background Because the ovarian follicle pool is established in utero, adverse exposures during this period may be especially impactful on the size and health of the initial follicle endowment, potentially shaping trajectories of ovarian follicle loss and
Maria E. Bleil, Paul English, Jhaqueline Valle, Nancy F. Woods, Kyle D. Crowder, Steven E. Gregorich, Marcelle I. Cedars   +6 more
doaj   +1 more source

Multiscale population dynamics in reproductive biology: singular perturbation reduction in deterministic and stochastic models [PDF]

arXiv, 2019
In this study, we describe different modeling approaches for ovarian follicle population dynamics, based on either ordinary (ODE), partial (PDE) or stochastic (SDE) differential equations, and accounting for interactions between follicles. We put a special focus on representing the population-level feedback exerted by growing ovarian follicles onto the
arxiv  

Ovarian volume throughout life: a validated normative model [PDF]

, 2013
The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and is under investigation as a screening tool for ovarian cancer.
arxiv   +1 more source

Oocyte maturation in the toad Rhinella arenarum (Amphibia, Anura): Evidence of cAMP involvement in steroid production and action [PDF]

, 2018
In this work, we describe the participation of the adenylate cyclase/3′-5′-cyclic adenonsine monophosphate (cAMP) pathway in the seasonal follicular secretion of progesterone (P 4 ) and testosterone (T), and its relationship with the maturation of ...
Arias Torres, Arias Torres, Canosa, Cerdá, Das, Deng, Eyers, Ferrell, Fortune, Gohin, Gohin, Hammes, Higashijima, Jalabert, Kamangar, Khan, Kwon, Kwon, Levin, Lin, Lin, Lubzens, Marteil, Medina, Miedlich, Nader, Nagahama, Norris, O'Brien, Pang, Pickford, Rasar, Romo, Sadler, Schuetz, Sen, Sen, Smith, Sánchez Toranzo, Sánchez Toranzo, Thomas, Voronina, Vu, White, Yamamoto, Yang, Zelarayán, Zelarayán, Zelarayán   +48 more
core   +1 more source

Compound Heterozygous Variants in ZSWIM7 Gene Linked to Infertility and Its Role in Gonadal Development

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT This study aims to elucidate the role of the ZSWIM7 gene in the etiology of infertility, focusing on its potential association with premature ovarian insufficiency and azoospermia. We investigated an 18‐year‐old female patient who presented with primary amenorrhea, hypoplasia of the uterus and ovaries, Tanner stage II breast and pubic hair ...
Denise M. Christofolini, Guilherme Pinn, Thainá Vilella, Maria I. Melaragno, Mariana Moysés‐Oliveira, Luciano Pompei, Rare Genomes Project Consortium, Bianca Bianco, Caio P. Barbosa   +8 more
wiley   +1 more source

Correlation between basal antral follicle count and mean ovarian diameter with ovarian responsiveness in art cycles

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2006
BACKGROUND & OBJECTIVE: Since, ovarian response during assisted reproductive technology (ART) depends on ovarian reserve so it is important to evaluate ovarian reserve before the ART cycle.
Z Basirat, G Riazi Arasi, S Esmaeil Zadeh, M Zeinal Zadeh, T Nazari   +4 more
doaj  

Patient level simulation and reinforcement learning to discover novel strategies for treating ovarian cancer [PDF]

arXiv, 2021
The prognosis for patients with epithelial ovarian cancer remains dismal despite improvements in survival for other cancers. Treatment involves multiple lines of chemotherapy and becomes increasingly heterogeneous after first-line therapy. Reinforcement learning with real-world outcomes data has the potential to identify novel treatment strategies to ...
arxiv  

Neonatal exposure to xenoestrogens impairs the ovarian response to gonadotropin treatment in lambs [PDF]

, 2015
Bisphenol A (BPA) and diethylstilbestrol (DES) are xenoestrogens which have been associated with altered effects on reproduction. We hypothesized that neonatal xenoestrogen exposure affects the ovarian functionality in lambs.
Belmonte, Norberto Miguel, Bosquiazzo, Veronica Lis, Luque, Enrique Hugo, Muñoz de Toro, Monica Milagros, Osti, Mario, Rivera, Oscar E., Rodriguez, Horacio Adolfo, Santamaría, Clarisa Guillermina, Varayoud, Jorgelina Guadalupe   +8 more
core   +2 more sources

Depression Symptom Trajectories in Mothers With the FMR1 Premutation Vary by CGG Repeat Length: A Longitudinal Study of 73 Women Spanning 20–75 Years of Age

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek, Lauren Jenner, Abigail L. Hogan, Laura Friedman, Elizabeth Berry‐Kravis, Flora Tassone, Tatyana Adayev, Amanda J. Fairchild, Jane E. Roberts   +8 more
wiley   +1 more source