Results 191 to 200 of about 170,341 (384)

Performance of Liquid Biopsy‐Based Multi‐Omics Biomarkers for Early Detection of Gynecological Malignancies: A Prospective Study (PERCEIVE‐I)

Advanced Science, EarlyView.
Following a comparative analysis of omics‐based cancer detection models, a novel liquid biopsy‐based multi‐omics combined model is developed for the early detection of gynecological malignancies. By integrating cell‐free DNA methylation and tumor protein markers, the combined model demonstrates high specificity and sensitivity and is uniquely designed ...
Zheng Feng, Huijuan Ge, Jingshu Wang, Yanan Wang, Xiaoran Sun, Bo Yang, Siyu Cao, Chenlian Quan, Qinhao Guo, Yusheng Han, Feidie Duan, Fang liu, Jing Zhao, Guoqiang Wang, Yuzi Zhang, Shangli Cai, Xiaohua Wu, Hao Wen   +17 more
wiley   +1 more source

Diagnosis of Ovarian Neoplasms Using Nomogram in Combination With Ultrasound Image-Based Radiomics Signature and Clinical Factors. [PDF]

Front Genet, 2021
Qi L, Chen D, Li C, Li J, Wang J, Zhang C, Li X, Qiao G, Wu H, Zhang X, Ma W.   +10 more
europepmc   +1 more source

Neuropeptide Y receptor expression in human primary ovarian neoplasms [PDF]

, 2003
Meike Körner, Beatrice Waser, Jean Claude Reubi   +2 more
openalex   +1 more source

Deciphering the Transcription Factor Landscape in Prostate Cancer Progression: A Novel Approach to Understand NE Transdifferentiation

Advanced Science, EarlyView.
The study deciphers the landscapes of lineage‐related transcription factors in prostatic adenocarcinoma and neuroendocrine prostate cancer using an innovative approach. These findings, validated across cohorts, highlight TFs' roles in cell development and offer novel therapeutic targets.
Yu Wang, Hui Xue, Xiaohui Zhu, Dong Lin, Zheng Chen, Xin Dong, Junru Chen, Mingchen Shi, Yuchao Ni, Jonathan Cao, Rebecca Wu, Connie Kang, Xinyao Pang, Francesco Crea, Yen‐Yi Lin, Colin C. Collins, Martin E. Gleave, Abhijit Parolia, Arul Chinnaiyan, Christopher J. Ong, Yuzhuo Wang   +20 more
wiley   +1 more source

Reducing Unnecessary Oophorectomies for Benign Ovarian Neoplasms in Pediatric Patients.

JAMA, 2023
Minneci PC, Bergus KC, Lutz C, Aldrink J, Bence C, Breech L, Dillon PA, Downard C, Ehrlich PF, Fallat M, Fraser JD, Grabowski J, Helmrath M, Hertweck P, Hewitt G, Hirschl RB, Kabre R, Lal DR, Landman M, Leys C, Mak G, Markel T, Pressey J, Raiji M, Rymeski B, Saito J, Sato TT, St Peter SD, Cooper J, Deans K, Midwest Pediatric Surgery Consortium.   +30 more
europepmc   +1 more source

Primary Fallopian Tube Carcinoma [PDF]

, 2011
Primary Fallopian Tube Carcinoma (PFTC) is rare and accounts for about 0.3% of all gynecologic cancers. Less than 1500 cases have been reported in the literature.
Bafna, UD, K, Balaiah, S, Gnana Prakash, Shetty, Prasad K   +3 more
core   +1 more source

Expression of BRCA1 protein in benign, borderline, and malignant epithelial ovarian neoplasms and its relationship to methylation and allelic loss of the BRCA1 gene [PDF]

, 2004
Cui-ju Wang, Akiko Horiuchi, Tsutomu Imai, Satoshi Ohira, Kazuko Itoh, Toshio Nikaido, Yoshihiko Katsuyama, Ikuo Konishi   +7 more
openalex   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

Advanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang, Runhua Zhou, Chengchao Xu, Lingyun Dai, Rui Hou, Liuhai Zheng, Chunjin Fu, Guangwei Shi, Jingwei Wang, Yang Li, Jinpeng Cen, Xiaolong Xu, Le Yu, Yilei Li, Jigang Wang, Qingfeng Du, Zhijie Li   +16 more
wiley   +1 more source

A novel immunohistochemical method for estimating cell cycle phase distribution in ovarian serous neoplasms: implications for the histopathological assessment of paraffin-embedded specimens [PDF]

, 2004
Ian Scott, T M Heath, Laurel S. Morris, Simon Rushbrook, K Bird, Sarah L. Vowler, Mark J. Arends, Nicholas Coleman   +7 more
openalex   +1 more source

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

Advanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare, Kshama Kundu, Papiya Dey, Krupa Thankam Philip, Nitish Chauhan, Muskan Sharma, Sankarsingh Kesharsingh Rajput, Birija Sankar Patro   +7 more
wiley   +1 more source