Results 231 to 240 of about 170,341 (384)

Sclerosing Stromal Tumor: A Rare Ovarian Neoplasm [PDF]

open access: gold, 2017
Shilpa Bairwa   +5 more
openalex   +1 more source

Enhancing the Protein Stability of an Anticancer VHH‐Fc Heavy Chain Antibody through Computational Modeling and Variant Design

open access: yesAdvanced Science, EarlyView.
In this study, a computational pipeline is developed to systematically evaluate the conformational stability, disulfide bond reduction state, and aggregation and degradation tendencies of an anticancer VHH‐Fc fusion antibody. Based on the mechanistic insights, antibody variants with enhanced stability and increased yield are successfully designed. This
Yuan Fang   +10 more
wiley   +1 more source

Female sexual function in bladder cancer: A review of the evidence

open access: yesBJUI Compass, Volume 4, Issue 1, Page 5-23, January 2023., 2023
Abstract Background Bladder cancer (BC) treatments are known to be invasive; nevertheless, research into the long‐term effects is limited and in the context of sexual function often male focussed. Female sexual dysfunction (FSD) has been reported in up to 75% of female patients.
Rebecca Martin   +7 more
wiley   +1 more source

Establishment of a Novel In Vitro and In Vivo Model to Understand Molecular Carcinogenesis of Endometriosis-Related Ovarian Neoplasms. [PDF]

open access: yesInt J Mol Sci
Sohel HI   +9 more
europepmc   +1 more source

34: A case of ovarian neoplasm and renal insufficiency with complete procidentia [PDF]

open access: bronze, 2017
Nina Jacobson   +3 more
openalex   +1 more source

Comparative Immunohistochemical Study of Galectins 1, 3 and 9 in Ovarian Epithelial Neoplasms [PDF]

open access: gold, 2020
Renata Margarida Etchebehere   +7 more
openalex   +1 more source

Targeting Antigen‐Presenting Cells to Enhance the Tumor‐Spleen Immunity Cycle through Liposome‐Neoantigen Vaccine

open access: yesAdvanced Science, EarlyView.
LNPsD18, a cationic liposome that enhances antigen‐presenting cell uptake in the spleen and tumor without targeting ligands is developed. Co‐delivering neoantigens and a TLR9 agonist significantly improve DC activation, tumor immunity, and survival in liver and colorectal cancer models, demonstrating the importance of dual‐site APC targeting for cancer
Yu Xu   +12 more
wiley   +1 more source

How germline genes promote malignancy in cancer cells

open access: yesBioEssays, Volume 45, Issue 1, January 2023., 2023
We hypothesize that activation of a “germline program” promotes oncogenesis. Expression of otherwise germline specific genes may result in pseudomeiotic activity, thereby promoting oncogenesis through genomic instability. Other processes that are differentially regulated in the germline, such as migration and epigenetic – and metabolic plasticity, may ...
Jan Willem Bruggeman   +4 more
wiley   +1 more source

scCompass: An Integrated Multi‐Species scRNA‐seq Database for AI‐Ready

open access: yesAdvanced Science, EarlyView.
scCompass integrates and standardizes transcriptomic data from ≈105 million single cells across 13 species, enabling the identification of stable expression genes and organ‐specific expression genes in humans and mice. It provides scalable datasets for AI model training, pretrained model checkpoints, and user‐friendly platforms for data sharing ...
Pengfei Wang   +29 more
wiley   +1 more source

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