Results 51 to 60 of about 553,624 (295)

Cytokines in peritoneal fluid of ovarian neoplasms

, 2020
The aim of this study was to evaluate cytokine levels (IL-2, IL-8, TNF-α, IL-5, IL-6 and IL-10) in the peritoneal fluid in non-neoplastic tumours, benign ovarian neoplasms and malignant ovarian neoplasms.
Agrimaldo Martins-Filho, Eddie Fernando Candido Murta, Rosekeila Simões Nomelini, Isac Souza Silva Rodrigues, Douglas Côbo Micheli, Cid Almeida de Lima, Beatriz Martins Tavares-Murta   +6 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Urinary cholesterol excretion in men with benign prostatic hyperplasia and carcinoma of the prostate [PDF]

, 1966
Urinary excretion of nonesterified (NEC) and total cholesterol (TC) has been investigated in 79 patients with prostatic adenoma (BPH) and 48 patients with carcinoma of the prostate.
P. GIORDANO, Odom, Lorrie F., Ruiz Jorge, Lissette, Williams, Fiona L. R., Llombart-Bosh, Antonio, Angelika, Pickel, McNeely, Lee K., McCarthy, Donna O., Roy, S., Meagher, David P., Jr., G. MAZZINI, Kumar, Lalit, Bhangui, G. R., Daniel, William E., Lloyd, Owen L., Tandon, P. N., Alegret Rodríguez, Milagros, Pickel, A., Kochupillai, V., Elsässer, Erich, Machado Puerto, Isidro, Karl, Hans Josef, E. TRAVERSI, Dua, Harsch, Stadler, Alexander, Cowpe, Jonathan G., Green, Michael, Jüngst, Dieter, Blake, Marilyn, Marx, Franz J., Poole, Marten A., Haase, Gerald M., Ogden, Graham R.; id_orcid, E. ASCARI, MONTECUCCO, CARLOMAURIZIO, A. RICCARDI, Moskowitz, M., Grill, J. P., G. IPPOLITI, Ingle, J. N., Stanley, R. J., Zimmerman, R. R., Kushner, H. D., Schild, S. E., Thompson, W. M., Schaid, D. J., Roche, P. C., Smart, C. R., Krammer, B., Buskirk, S. J., Holleb, A. I., McLelland, R., INVERNIZZI, ROSANGELA, Van Wijnen, Andre J., Su, J. Q., Lian, Jane B., Shapiro, Stephanie, Krook, J. E., Maihle, N. J., Olsen, K. D., M. DANOVA, M. GIRINO, Fragoyannis, S, Costanza, Mary E., Foote, R. L., Stein, Janet L., F. PASQUALI, Henson, D. E., Witzig, T. E., Kunselman, S. J., Wall, James, Hartmann, L. C., G. UCCI, Hutter, R. V., Kung'u, A., Wold, L. E., Farr, G. H., Sperry, Kris, Yalcin, S, Stein, Gary S., Pollack, Alan, Zagars, Gunar K, Kavadi, Vivek S   +82 more
core   +2 more sources

CLINICOPATHOLOGICAL STUDY OF OVARIAN NEOPLASMS – AN INSTITUTIONAL PERSPECTIVE [PDF]

, 2022
Objective: The objective of the study was to know the frequency and histomorphological patterns of ovarian neoplasms concerning age. Methods: A 2-year retrospective study was done in the pathology department, GITAM Institute of Medical Sciences and ...
CHERUKURI, PRASANTHI, GARDAS, VASUNDARA, SALOMI, SUMERA   +2 more
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

COMPARATIVE EFFECTIVENESS OF MODERN METHODS OF DIFFERENTIAL DIAGNOSIS OF OVARIAN NEOPLASMS

Мать и дитя в Кузбассе, 2018
The aim of the research – to identify the most informative methods of differential diagnosis of ovarian neoplasms at the preoperative stage. Materials and methods. The study involved 117 patients with ovarian neoplasms.
Мария Алексеевна Егунова, Ирина Георгиевна Куценко, Алла Ивановна Дмитриева, Лидия Валентиновна Пикалова, Елена Александровна Кунгурова, Наталья Александровна Василенко   +5 more
doaj  

Immunohistochemistry: A diagnostic aid in differentiating primary epithelial ovarian tumors and tumors metastatic to the ovary

South Asian Journal of Cancer, 2013
Introduction: Among cancers of the female genital tract, the incidence of ovarian cancer ranks below only carcinoma of the cervix and the endometrium. Recent years have witnessed significant development in the use of immunohistochemistry in diagnostic ...
Divya Kriplani, Mandakini M Patel
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Identification and characterization of a homozygous deletion found in ovarian ascites by representational difference analysis [PDF]

, 1999
We have performed representational difference analysis (RDA) on DNA from tumor cells and normal fibroblasts isolated from the ascites of a patient with ovarian cancer. Five of six products of the RDA were homozygously deleted from the tumor DNA.
Perry, P, Morrison, H, Gabra, H, Taylor, K J, Watson, J E, Porteous, D J, Rabiasz, G J, Smyth, J F   +7 more
core  

Pancreaticobiliary metastasis presenting as primary mucinous ovarian neoplasm: A systematic literature review

Gynecologic Oncology Reports, 2019
True primary mucinous ovarian carcinomas are rarer than originally thought and their clinical behavior and treatment response are different than more common epithelial ovarian carcinomas.
Sarah A. Ackroyd, Lauren Goetsch, Jennifer Brown, Karen Houck, Congli Wang, Enrique Hernandez   +5 more
doaj   +1 more source