Results 191 to 200 of about 26,707 (256)

GADD45A is Essential for Granulosa Cells Differentiation and Ovarian Reserve in Human and Mice. [PDF]

J Cell Mol Med
Guo J, Hu Y, Cao Q, Zhang Y, Jia Y, Liu L, Zeng Y, Wu X, Song Y, Yang M, Xu W, Hu Y, Huang W, Tang T.   +13 more
europepmc   +1 more source

Living at genetic risk: The patient experience of Lynch syndrome

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome is a germline cancer predisposition syndrome caused by a variant in one of four genes. Lynch syndrome places individuals at significantly higher risk for a range of cancers, especially colorectal and endometrial. Depending on which gene is affected, the risk of ovarian, gastric, small bowel, pancreatic, biliary urothelial, brain,
Nicola Reents, Georgina Hoffmann, Kelly Kohut   +2 more
wiley   +1 more source

Association between healthy beverage index and odds of diminished ovarian reserve in a case-control study. [PDF]

Sci Rep
Khodarahmi M, Balali A, Vajdi M, Ghasemi-Tehrani H, Askari G, Ghavami A.   +5 more
europepmc   +1 more source

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Bushen Zhuluan Decoction alleviates diminished ovarian reserve by regulating the m⁶A modification of PLGF. [PDF]

J Ovarian Res
Liang H, Tang P, Du Q, Chen X, Wang L.
europepmc   +1 more source

Comparing the effectiveness of prostate cancer screening protocols: European Association of Urology– and European Randomized Study of Screening for Prostate Cancer–based strategies

International Journal of Cancer, EarlyView.
What's New? Although screening reduces prostate cancer mortality, concerns about overdiagnosis and unnecessary biopsies have given rise to more tailored strategies. The European Association of Urology (EAU) proposed a risk‐adapted screening strategy combining prostate‐specific antigen (PSA)‐based intervals, a risk calculator, and magnetic resonance ...
Zhenwei Yang, Luuk A. van Duuren, Monique J. Roobol, Nicole S. Erler, Dimitris Rizopoulos, Eveline A. M. Heijnsdijk   +5 more
wiley   +1 more source

Transdermal testosterone gel vs placebo in women with diminished ovarian reserve prior to in vitro fertilization: a randomized, clinical trial. [PDF]

Nat Commun
Polyzos NP, Leathersich SJ, Martínez F, Blockeel C, Gosálvez A, de la Fuente L, Pinborg A, Fàbregues F, Stoop D, Rodriguez I, de Geyter C, Davis SR, Humaidan P.   +12 more
europepmc   +1 more source

Tumor‐educated platelets in cancer diagnostics and prognostics: A critical appraisal and roadmap for clinical translation

International Journal of Cancer, EarlyView.
Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon, Min‐Kyung Lee, Eunyong Ahn, Heeyeon Kim, Yong Sang Song, Taejin Ahn   +5 more
wiley   +1 more source

Diminished Ovarian Reserve: A Narrative Review of Etiologies and Possible Therapeutic Approaches. [PDF]

J Menopausal Med
Lee DY.
europepmc   +1 more source