Results 161 to 170 of about 248,803 (285)

Changes in ovarian hardness and elasticity affect the development and function of secondary follicles. [PDF]

Sci Rep
Kawai T, Shimada M.
europepmc   +1 more source

B4GALNT4‐Mediated Glycosylation of PDK1 Activates the PI3K‐AKT Signaling Pathway to Promote Prostate Cancer Progression

Advanced Science, EarlyView.
This study identifies B4GALNT4 as a key driver of prostate cancer (PCa). It shows that B4GALNT4 glycosylates PDK1 protein at the N531 site, which stabilizes the PDK1 and constitutively activates the PI3K‐AKT pathway. This mechanism promotes tumor cell proliferation, migration, and invasion. The findings establish the B4GALNT4‐PDK1 glycosylation axis as
Shaoqin Jiang, Mengqiang Li, Qingfu Su, Ruiling Dou, Shaoshan Lin, Jili Zhang, Xiaochen Sun, Haolan Yu, Wei Bao, Min Qu, Yan Wang, Chenghua Yang, Xu Gao   +12 more
wiley   +1 more source

Single-cell transcriptomics of chicken ovarian cancer identifying immune subsets with prognostic implications. [PDF]

Poult Sci
Zhu G, Wang SCY, Yao H, He J, Zhang J, Zhang M, Wang Y.   +6 more
europepmc   +1 more source

Comparison of the ovarian and uterine reproductive parameters, and the ovarian mRNA and protein expression of LHR and FSHR between the prepubertal and adult female cats [PDF]

, 2017
Chowdhury, Ishibashi, Johnston, Mehl, Misrahi, Ponglowhapan, Saint-Dizier   +6 more
core   +2 more sources

Cellular Snowballing: Cell Adhesion and Migration Drive the Self‐Assembly of Cell‐Microgel Biohybrid Spheroids

Advanced Science, EarlyView.
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie, Sina Kheirabadi, Changhao Li, Aneesh Risbud, Aswathy Sebastian, Istvan Albert, Sulin Zhang, Amir Sheikhi   +7 more
wiley   +1 more source

A male-pheromone-elevated transcription factor ZNF362.1 in female schistosomes determines sexual maturation. [PDF]

Sci Adv
Gu M, Cheng W, Li S, Chen G, Chen X, Jiang R, Yuan M, Wang J, Zhang W, Yi C, Xie Y, Wang X, Hu W, Wang J.   +13 more
europepmc   +1 more source

Inhibition of SLC11A1‐Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke

Advanced Science, EarlyView.
Genetic and pharmacological inhibition of SLC11A1 functioning as an H+/Fe2+ antiporter–mediated lysosomal iron accumulation in microglia promotes lysosomal lumen acidification, increases CTSD expression, enhances lysosomal myelin debris uptake and degradation, and promotes repair following white matter stroke. ABSTRACT White matter stroke (WMS) results
Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao   +11 more
wiley   +1 more source

Ovary

, 2008
John B. Heppner, John B. Heppner, Minos E. Tzanakakis, Minos E. Tzanakakis, Minos E. Tzanakakis, Pauline O. Lawrence, John L. Capinera, Rod Nagoshi, Günter Gerlach, Hugh Smith, John L. Capinera, John B. Heppner, John B. Heppner, James L. Nation, Alan A. Berryman, Simon R. Leather, John B. Heppner   +16 more
  +4 more sources

Inflammatory bowel disease leads to long-term ovarian dysfunction via immune-mediated follicular aging. [PDF]

Cell Mol Life Sci
Guo X, Liu Y, Zhao H, Liu J, Li Y, Li J, Liu J, Ma T, Lin L, Liu X, Kong J, Lin J, Zhao D, Chong CH, Xie X, Chiu PCN, Zhang Q.   +16 more
europepmc   +1 more source

IGF‐1 Deficiency Serves as an Integrated Biomarker Pathogenic Driver and Predictor in Poor Ovarian Response

Advanced Science, EarlyView.
IGF‐1 deficiency underlies poor ovarian response (POR), as reduced levels in follicular fluid and granulosa cells impair antral follicle formation and compromise reproductive outcomes. Including IGF‐1 as a biomarker significantly enhances the accuracy of models predicting both PORrisk and pregnancy success.
Zhu Hu, Yuanyuan Yu, Guanyou Huang, Jinnan Li, Chao Yang, Aizhuan Long, Jia Tang, Tengxiang Chen, Shuyun Zhao, Tuo Zhang   +9 more
wiley   +1 more source