Advances in GPCRs Associated With Wnt Signaling Within the Auditory System
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang +3 more
wiley +1 more source
Multi-Probing Opportunistic Routing in Buffer-Constrained Wireless Sensor Networks. [PDF]
Sun N, Cao S, Liu X, Gao Y, Xu Y, Liu J.
europepmc +1 more source
This review highlights how Phytophthora sojae utilizes unconventional lineage‐specific signaling networks, including unique G protein‐coupled receptor fusions, expanded kinases, and rapidly evolving effectors, to infect soybeans. Understanding these divergent molecular paradigms reveals critical vulnerabilities in this destructive pathogen, offering ...
Min Qiu +4 more
wiley +1 more source
Elucidating the reversed proton relay mechanism: dual regulatory role of pendant carboxylates relevant to water oxidation. [PDF]
Liu T +7 more
europepmc +1 more source
Beyond natural variation: The era of rational design in plant immunity
Abstract The evolutionary arms race between crops and pathogens has reached a critical impasse: pathogen adaptation consistently outpaces the development of resistant varieties through conventional breeding. This growing imbalance highlights the need to move beyond the exclusive reliance on natural variation toward more predictive and design‐oriented ...
Hengjing Li +3 more
wiley +1 more source
EACCO: Optimizing the Computation and Communication in Resource-Constrained IoT Devices for Energy-Efficient Swarm Robotics. [PDF]
Ijaz A +4 more
europepmc +1 more source
Brokering Localization: Country‐Based Pooled Funds in Humanitarian Assistance
ABSTRACT This article analyzes Country‐Based Pooled Funds (CBPFs) to identify types of brokerage models and their effects on localization. CBPFs are intermediaries in the aid chain connecting donors to implementers such as the United Nations, international non‐governmental organizations (INGOs) and national NGOs (NNGOs). This paper analyzes four of the
Maryam Zarnegar Deloffre
wiley +1 more source
Adaptive Sliding‐Mode Control of a Perturbed Diffusion Process With Pointwise In‐Domain Actuation
ABSTRACT A sliding mode–based adaptive control law is proposed for a class of diffusion processes featuring a spatially‐varying uncertain diffusivity and equipped with several point‐wise actuators located at the two boundaries of the spatial domain as well as in its interior.
Paul Mayr +3 more
wiley +1 more source
The cerebro-pelvic axis: a unified framework linking higher brain function, pelvic floor control, and lower urinary tract dysfunction. [PDF]
Li Z, Fu J, Pu J, Qian Y, Gai X, Li L.
europepmc +1 more source
Sliding Mode Control in Aerospace Applications: A Survey
ABSTRACT Sliding mode control (SMC) enjoys robustness to matched and unmatched (in the case of minimum phase input‐output dynamics) bounded perturbations, and finite time convergence. Second‐order and higher‐order sliding mode control systems (2‐SMC/HOSMC) retain all the advantages of sliding mode control, but in addition can be applied to systems of ...
Yuri Shtessel, Christopher Edwards
wiley +1 more source

