Results 211 to 220 of about 19,520,789 (348)

Effects of different blood storage conditions on leukocytes cell population data using the Sysmex XN hematological analyzer. [PDF]

Biochem Med (Zagreb)
Roccaforte V, Panella R, Daves M, De Martino A, Jani E, Sabbatini G, Agostini P, De Filippi F, Formenti P, Lippi G, Vidali M, Pezzi A, Pastori S.   +12 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Development and Performance Evaluation of Composite Modified Nano-TiO₂ for Permeable Asphalt Mixtures: Focus on Exhaust Degradation and Dispersion Properties. [PDF]

Materials (Basel)
Li Y, Zhang S, Xi D, Li P, Zhang K, Zhu Y.   +5 more
europepmc   +1 more source

Realization of Combined Chromatic Dispersion Compensation Methods in High Speed WDM Optical Transmission Systems

Chromatic dispersion (CD) has a significant impact on a quality of transmitted optical signal in high-speed fiber optic communication systems with data rates up to 10 Gbit/s, and as a result CD limits the maximum length of transmission distance. In order
Bobrovs, Vjačeslavs, Spolītis, Sandis, Ivanovs, Ģirts   +2 more
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Performance of Dispersion Models in Predicting Ambient Ethane Concentrations at a Regional Air Quality Monitor in an Oil- and Gas-Producing Region. [PDF]

ACS Environ Au
Graves JD, Kimura Y, Modi M, Stokes S, Meyer M, Hildebrandt Ruiz L, Allen DT.   +6 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

London Dispersion Governs Stereochemistry, Stability, and Self-Sorting in a System of M₄L₄ Cages. [PDF]

J Am Chem Soc
Massad I, Dobson JTF, Teeuwen PCP, Ronson TK, Nitschke JR.   +4 more
europepmc   +1 more source

Accounting for Individual Over-Dispersion in a Bonus-Malus Automobile Insurance System

ASTIN Bulletin: The Journal of the International Actuarial Association, 1999
Shengwang Meng, Yuan Wei, G. A. Whitmore
semanticscholar   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source