Results 41 to 50 of about 7,449,685 (312)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Electrostatic Discharge (ESD) and Electrical Overstress (EOS): The state of the art in components to systems

open access: yesEngineering and Applied Science Research, 2017
Electrostatic Discharge (ESD), Electrical Overstress (EOS) and electromagnetic compatibility (EMC) continue to impact semiconductor manufacturing, semiconductor components and systems as technologies scale from micro- to nano-electronics.
Steven H. Voldman
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

Molecular mechanisms of the coupling of gating to voltage sensing in transmembrane proteins [PDF]

open access: yes, 2014
Voltage gated potassium ion (Kv) channels regulate action potentials of the nervous system by responding to changes in transmembrane voltage, enabling K+ transport across the membrane to restore cells to their resting potential.
Starek, Greg
core   +1 more source

Selection and Application of DC Support Capacitor in Power Converter

open access: yesKongzhi Yu Xinxi Jishu, 2011
It introduces the advantages and disadvantages of electrolytic capacitor and metalized film capacitor in various circuit topologies of power converters, describes application notices of the capacitor in detail and presents the specific design parameters ...
TANG Haiyan, TANG Zhou
doaj  

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Grid Connected Inverter Behavior with an Output LC Filter under Voltage Sag Operation [PDF]

open access: yes, 2009
The aim of this paper is to propose an over current limitation and voltage control strategy for a grid connected inverter with a LC output filter used in distributed generation and in case of voltage sag.
COLAS, Frédéric   +2 more
core  

Design of the IGBT Snubber Circuit for Megawatt Level Wind Power Module

open access: yesKongzhi Yu Xinxi Jishu, 2016
It introduced the theoretical analysis and calculation of snubber circuit for megawatt level wind power module, and demonstrated the suppressing effect of snubber capacitor on over-voltage. Simulation results approved that ripple currents and temperature
ZHAI Long   +5 more
doaj  

Sequences selection research on over-voltage and over-current protection for intrinsic safety power supply

open access: yesGong-kuang zidonghua, 2019
Over-voltage and over-current protection are two forms of over-voltage and over-current protection sequences of intrinsic safety power supply. In order to study the influence of different protection sequence forms on safety performance of intrinsic ...
BAO Changjun   +4 more
doaj   +1 more source

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