Results 91 to 100 of about 757,728 (303)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Every electrical system in solar panel can fail during electrical faults. In this incidence, high fault current can occur. Such current must be interrupted by a protective system. The research was supported by experimental tests. In work conditions close
Ameur menad Chawki +2 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Research on transient energy suppression strategy of intrinsically safe output power supply for mine
In response to the requirements of GB/T 3836.4—2021 Explosive atmosphere Part 4: Equipment with protection by intrinsic safety “i” for outputting transient energy of intrinsically safe power sources based on the principle of semiconductor rapid short ...
Changna GUO
doaj +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
ANALYSIS OF OVER CURRENT RELAY AND GROUND FAULT RELAY PROTECTION SYSTEM IN SUB-STATION SP-2 TANAH MIRING USING RELAY COORDINATION WITH ETAP BASED [PDF]
Soetjipto Soewono, Enni Noprianti
openalex +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
ELECTRONIC FUSE USING RESETTABLE POLY FUSE FOR OVER CURRENT PROTECTION
Shivam Junghare
openalex +1 more source
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source

