Results 141 to 150 of about 502,761 (308)

Deaths and hospitalizations resulting from poisoning by prescription and over-the-counter drugs in Brazil. [PDF]

open access: yesRev Saude Publica, 2021
Duarte FG   +4 more
europepmc   +1 more source

Manifold-Marketing:a new marketing archetype for the information age, applied to the adoption of oral contraceptives and other drugs by end-users [PDF]

open access: yes, 2013
Taking into account the new communication paradigm of Social Media this paper proposes an original marketing archetype for the information age named by the authors as “ManifoldMarketing”.
Lopes, José   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Self-Medication: Awareness and Attitude Among Undergraduate Medical Students in A Tertiary Care Medical College, Dhule

open access: yesNational Journal of Community Medicine, 2015
Background: The practice of self-medication is becoming more common worldwide and currently plays a major role in self-care. The objectives of our study were to determine the perception and level of awareness regarding over the counter over the counter (
Sandip Bharat Patil
doaj  

Over the counter drugs and self-medication: A worldwide paranoia and a troublesome situation in India during the COVID-19 pandemic. [PDF]

open access: yesAnn Med Surg (Lond), 2022
Ray I   +9 more
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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