Results 151 to 160 of about 563,471 (308)
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Application of Analog Adaptive Filters for Dynamic Sensor Compensation
This paper investigates the application of analog adaptive techniques to the area of dynamic sensor compensation, of which there is little reported work in the literature. The case is illustrated by showing how the response of a load cell can be improved
White, Neil M. +2 more
core
Research on Suppression of IGBT’s Turn-off Over-voltage for a Wind Power Converter
IGBT’s turn-off over-voltage suppression is an important research topic of converters. This paper analyses the advantages and disadvantages of various suppression methods through comparison, and then obtains the basic conclusion that active clamping is ...
OUYANG Liu, LI Hua, YANG Guang, YANG Tao
doaj
ELECTRICAL CIRCUITS PROTECTION AGAINST UNDER VOLTAGE OR OVER VOLTAGE
Rama Rao Lachanna, Lawrence Arokiasamy
openaire +1 more source
Over voltage protection device for ROV
Supplying power to equipment always imposes a risk of damaging it. This risk is apparent in every application whether it be an industrial or a home appliance. One of these harmful occurrences is something like lightning which introduces a potentially harmful voltage in the system.
Kantzon, David, Lahti, Sebastian
openaire +1 more source
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Impact of atmospheric conditions on the flash-over voltage of the transmission line insulators using central composite design. [PDF]
Ghaly RNR +6 more
europepmc +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source

