Results 111 to 120 of about 175,097 (273)

Evaluation and management of overactive bladder: strategies for optimizing care

, 2016
Marcella G Willis-Gray, Alexis A Dieter, Elizabeth J Geller Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA Abstract ...
Willis-Gray MG, Dieter AA, Geller EJ
core  

Non‐Invasive Triage of Bladder Outlet Obstruction and Detrusor Underactivity in Men With Lower Urinary Tract Symptoms: A Narrative Review and Conceptual Framework for Depth‐Aware Multimodal Transcutaneous Testing

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Differentiating bladder outlet obstruction (BOO) from detrusor underactivity (DU) remains a major unmet need in the management of lower urinary tract symptoms in men. Although pressure–flow urodynamics provide a definitive physiological classification, their invasiveness limits their widespread use.
Sehwan Kim, Bryan K. Kim, John T. Stoffel, Aram Kim   +3 more
wiley   +1 more source

New technologies in the management of overactive bladder: current research and future prospects

Therapeutic Advances in Urology, 2019
Overactive bladder is characterized by frequency, urgency (wet or dry) and nocturia. These troublesome symptoms incur both a physiologic and economic cost, expected to be in excess of US$82 billion in the USA and Europe by the year 2020.
Serge P. Marinkovic
doaj   +1 more source

P2X₃ Knock-Out Mice Reveal a Major Sensory Role for Urothelially Released ATP [PDF]

, 2001
The present study explores the possible involvement of a purinergic mechanism in mechanosensory transduction in the bladder using P2X₃ receptor knock-out (P2X₃ ⁻⁄⁻) and wild-type control (P2X₃ ⁺⁄⁺) mice.
Bodin, P, Cockayne, DA, Kasakov, L, Burnstock, G, Rong, W, Bardini, M, Ford, APDW, Vlaskovska, M   +7 more
core  

Diabetes‐Induced Dysregulation of Purinergic Signaling in the Bladder Mucosa: Accelerated ATP Hydrolysis and Impaired Adenosine Uptake Promote Underactive Bladder Phenotype

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To explore molecular mechanisms underlying excessive extracellular adenosine (ADO) accumulation in the bladder lamina propria (LP) of mice with type 2 diabetes (T2D) induced by a high‐fat, high‐sucrose diet (HFHSD), conceivably leading to bladder underactivity.
Mahsa Borhani Peikani, Brian A. Perrino, Violeta N. Mutafova‐Yambolieva   +2 more
wiley   +1 more source

Risk of dementia associated with anticholinergic drugs for overactive bladder in adults aged ≥55 years: nested case-control study [PDF]

Objective To investigate whether different anticholinergic drug treatments for overactive bladder have differential risks for incident dementia, in a large representative population of older adults in England.Design Nested case-control study.Setting ...
Dening, Tom, Coupland, Carol, Orrell, Martin, Avery, Tony, Bell, Brian, Iyen, Barbara   +5 more
core   +1 more source

One Size Does Not Fit All: Establishing Anticipated Baseline Intravesical Pressures Adjusted for Position and Body Mass Index

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose Accurate measurement of intravesical pressure (Pves) during multichannel urodynamic testing requires zeroing with reference to surrounding atmosphere, establishing a reference level for measuring Pves, and assessing response to coughs.
Parker Holum, Soutik Ghosal, Lucie T. Lefbom, Jacqueline Zillioux, David N. Martin, Marieke K. Jones, Mikel Gray   +6 more
wiley   +1 more source

Zeroing Pressures in Urodynamics: Revisiting Current Practice and Pressure Interpretation

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Zeroing of pressure transducers is a fundamental step in urodynamic testing, as it affects pressure tracings and numerical values. Atmospheric zeroing before catheter insertion is the recommended approach, but zeroing with catheters in situ is also used.
Lucas Antonio Pereira do Nascimento, Vicktor Bruno Pereira Pinto, Carlos Henrique Costa, Cristiano M. Gomes   +3 more
wiley   +1 more source

Sacral neuromodulation in overactive bladder: a review and current perspectives

, 2016
Troy Sukhu,1 Michael J Kennelly,2 Raj Kurpad1 1Department of Urology, University of North Carolina, Chapel Hill, 2Department of Urology, Carolinas Medical Center, Charlotte, NC, USA Abstract: Overactive bladder (OAB) symptoms of urgency, frequency, and ...
Kennelly MJ, Sukhu T, Kurpad R
core  

One‐Year Transcutaneous Tibial Nerve Stimulation Treatment Persistence in Lower Urinary Tract Dysfunction: Clinical and Urodynamic Associated Factors in a Prospective Observational Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims To assess 1‐year Transcutaneous Tibial Nerve Stimulation (TTNS) treatment persistence in routine clinical care and to explore clinical and urodynamic factors associated with treatment persistence in patients with lower urinary tract dysfunction (LUTD).
Damien Prat, Evelyne Castel‐Lacanal, Thibaut Brierre, Gaetane Foures, Camille Cormier, Xavier De Boissezon, David Gasq, Philippe Marque, Xavier Gamé, Emmeline Montané   +9 more
wiley   +1 more source