Results 151 to 160 of about 175,097 (273)

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Mirabegron – a selective ß3-adrenoreceptor agonist for the treatment of overactive bladder

Research and Reports in Urology, 2012
Alka A Bhide, G Alessandro Digesu, Ruwan Fernando, Vik KhullarDepartment of Urogynaecology, St Mary's Hospital, London, United KingdomAbstract: Overactive bladder is a common condition that significantly impacts overall quality of life ...
Bhide AB, Digesu GA, Fernando R, Khullar V   +3 more
doaj  

Visual, vestibular, and ocular motor changes during nitroglycerin‐triggered vestibular migraine

Headache: The Journal of Head and Face Pain, EarlyView.
Plain Language Summary Vestibular migraine (VM) is a common cause of intermittent dizziness, but there have been no studies with provoked (induced) VM used to characterize how the vestibular and ocular (vision) systems interact. We injected 20 patients with VM with nitroglycerin to provoke an attack and used a specialized camera to record their eye ...
Maria Dolores Villar‐Martinez, Francesca Puledda, Caroline Domingos‐Belo, Adolfo M. Bronstein, Peter J. Goadsby   +4 more
wiley   +1 more source

Expanding the Clinical Spectrum of DHX30‐Related Neurodevelopmental Disorder: A Case Report and a Scoping Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Whole exome sequencing (WES) has improved diagnostic rates for neurodevelopmental disorders (NDDs) while introducing challenges in novel variant interpretation. DHX30‐related NDD (DHX30‐NDD) is a recently described condition with an evolving phenotypic spectrum.
Nattaporn Tassanakijpanich, Areerat Hnoonual, Oradawan Plong‐On, Pornprot Limprasert   +3 more
wiley   +1 more source

Sleep in Trans and Non‐Binary Individuals: A Question of Gender?

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep problems are increasingly prevalent in society. One group that is disproportionately affected includes transgender and non‐binary individuals, whose sex assigned at birth does not match their identified gender. This mismatch can lead to gender minority stress and increases the risk of mental disorders.
Lieve Thecla van Egmond, Antonia Wilhelm, Nora Naib Majani, Birgit Derntl   +3 more
wiley   +1 more source

Implantable tibial neuromodulation with an Anklet for overactive bladder: a review. [PDF]

World J Urol
Timmermans JF, Heesakkers JPFA.
europepmc   +1 more source

Targeting Orexin 2 Receptors in Idiopathic Hypersomnia and Narcolepsy: A Randomised Phase 1b Proof‐Of‐Concept Study of Alixorexton

Journal of Sleep Research, EarlyView.
Orexin 2 receptor agonists have demonstrated that targeting the orexin system may address symptoms of central disorders of hypersomnolence. Results of this phase 1 study support the phase 2 clinical evaluation of oral alixorexton in patients with IH, NT2 and NT1.
Ronald R. Grunstein, Brendon J. Yee, Julia L. Chapman, Jian Eu Tai, Sheila Sivam, Craig Hopkinson, Daniel G. Smith, Alexandra Lovett, Shifang Liu, Sergey Yagoda, Bhaskar Rege   +10 more
wiley   +1 more source

Can you have a SMALL bladder? (or an Overactive Bladder)?

, 2018
Can you have a "small bladder" or what is an Overactive Bladder? Why do some people need to go to the bathroom/toilet more often than others? Why am I always having to pee? Is there such a thing as having a small bladder? What is This video outlines some
Moro, Christian; id_orcid
core   +1 more source

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

Overactive Bladder Medication Access

IMPORTANCE: The price range, insurance coverage, and side effect burden of overactive bladder medications is broad and varied. An internal quality improvement project was undertaken to improve patient ability to access and ultimately adhere to preferred ...
Foust-Wright, Caroline, Courbron, Yanghee   +1 more
core   +1 more source