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Overactive bladder in women

Nursing Standard, 2016
Overactive bladder in women is a common chronic condition of urinary storage, affecting a significant proportion of the population. It is defined as a symptom diagnosis that indicates lower urinary tract dysfunction, in which patients experience urinary urgency, with or without urge incontinence, usually accompanied by frequency and nocturia.
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Refractory Overactive Bladder

2021
Overactive bladder (OAB) is a prevalent health issue that affects millions of people of all ages around the world. OAB comprises a constellation of symptoms that includes urinary frequency and urgency with or without urgency incontinence and can have a tremendous impact on an individual's quality of life.
openaire   +1 more source

Neuromodulation for overactive bladder

Nature Reviews Urology, 2013
Overactive bladder (OAB) affects millions of people worldwide yet first-line treatments are often poorly tolerated and compliance rates are low. Neuromodulation works via afferent nerve modulation and offers a minimally invasive and reversible alternative treatment option for patients with OAB who have failed first-line therapy.
Jamie, Bartley   +2 more
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Oxybutynin and the overactive bladder

World Journal of Urology, 2001
Oxybutynin is a tertiary amine, which undergoes an extensive first-pass metabolism. It has an active metabolite, N-desethyl oxybutynin, and the effect of oral oxybutynin is to a large extent exerted by this metabolite. Oxybutynin has both an antimuscarinic and a direct muscle relaxant effect, and, in addition, local anesthetic actions.
K E, Andersson, C R, Chapple
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Basic and clinical aspects of antimuscarinic agents used to treat overactive bladder

Pharmacology and Therapeutics, 2018
Antimuscarinic agents are now widely used as the pharmacological therapy for overactive bladder (OAB) because neuronal (parasympathetic nerve) and non‐neuronal acetylcholine play a significant role for the bladder function.
S. Yamada   +4 more
semanticscholar   +1 more source

Solifenacin: Treatment of overactive bladder

Drugs of Today, 2004
An investigational muscarinic antagonist, solifenacin is indicated in the treatment of overactive bladder. Solifenacin works to decrease bladder activity by inhibiting contraction of the smooth muscle wall surrounding the bladder. Micturition normally occurs following stimulation of acetylcholine muscarinic M3 receptors within the detrusor muscle wall.
Chilman Blair, K, Bosch, Ruud
openaire   +3 more sources

Bladder Sensation Measures and Overactive Bladder

Journal of Urology, 2009
We performed a prospective multicomponent study to determine whether subjective and objective bladder sensation instruments may provide data on sensory dysfunction in patients with overactive bladder.We evaluated 70 prospectively enrolled patients with urodynamics and questionnaires on validated urgency (Urgency Perception Score), general overactive ...
David E, Rapp   +3 more
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Overactive Bladder and Hyperlipidemia

Female Pelvic Medicine & Reconstructive Surgery, 2011
: To determine the relationship between overactive bladder (OAB), with or without urinary incontinence (UI), and hyperlipidemia.: A random sample of 8077 primary care patients were recruited for the General Longitudinal Overactive Bladder Evaluation.
Sheila V, Garnica   +3 more
openaire   +2 more sources

Overactive bladder in the elderly

Urologiia
Overactive bladder (OAB) is a syndrome consisting of urgency, usually accompanied by urinary frequency and nocturia, with or without urgent incontinence, in absence of a causative infection or pathological conditions. The prevalence of OAB is approximately 11-19% in both men and women, and leads to a significant negative effect on health-related ...
G, Krivoborodov G   +4 more
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Bladder afferents and their role in the overactive bladder

Urology, 2002
The role of afferent innervation of the bladder in the pathophysiology of urinary incontinence has become the focus of intense interest. In normal health, the afferent pathway is mediated largely by Adelta-fibers, which ultimately send information about the state of bladder fullness to the pontine micturition center via the periaqueductal gray matter ...
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