Results 171 to 180 of about 20,464,759 (310)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Osteopathic Manipulative Treatment for Asthma: A Systematic Review of Objective Pulmonary Function Outcomes. [PDF]

Cureus
Ponce A, Perrine O, Heintzelman KA.
europepmc   +1 more source

Interim overall 6G system design

This report will provide an initial design of the overall 6G system. The technical enablers and components developed from other SNS Stream B projects will be considered in addition to those developed in Hexa-X-II. This report will also contain an initial description of the WP2 (T2.2-T2.4) components, that will be considered with other selected ...
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Digital Inclusion Pathways for Older Chinese Adults in the Context of Active Aging: Secondary Analysis of 2023 China Longitudinal Aging Social Survey Data. [PDF]

JMIR Aging
Zhao B, Wang X, Chen R, Nam EW.
europepmc   +1 more source

The Danish Randomized Lung Cancer CT Screening Trial—Overall Design and Results of the Prevalence Round

Journal of Thoracic Oncology, 2009
J. Pedersen, H. Ashraf, A. Dirksen, K. Bach, H. Hansen, P. Toennesen, H. Thorsen, J. Brodersen, B. Skov, M. Døssing, J. Mortensen, K. Richter, P. Clementsen, N. Seersholm   +13 more
semanticscholar   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Prevalence and Associated Factors of Developmental Delays Across Gross Motor, Fine Motor, Language and Social Domains in Malaysian Children Aged 6-59 Months. [PDF]

Child Care Health Dev
Nasaruddin NH, Awaluddin SM, Alias N, Wan-Fei K, Wan TS, Shawaluddin NS, Anera SNS, Zain SH, Zainudin AH, Hasani WSR.   +9 more
europepmc   +1 more source

Draft overall 5G RAN design

This deliverable will contain draft considerations on an overall RAN design, building upon deliverables D 3.1, D 4.1, D 5.1 and D 6.1, and providing a summary of the current status of the key innovation pillars in the METIS-II project. The deliverable will also provide answers to the key 5G RAN design questions posed in Section 1.2.
openaire   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source